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Core binding factor information


The Core binding factor (CBF) is a group of heterodimeric transcription factors.

Core binding factors are composed of:

  • a non-DNA-binding CBFβ chain (CBFB)
  • a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)

and 21 Related for: Core binding factor information

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Core binding factor

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The Core binding factor (CBF) is a group of heterodimeric transcription factors. Core binding factors are composed of: a non-DNA-binding CBFβ chain (CBFB)...

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RUNX1

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Runt-related transcription factor 1 (RUNX1) also known as acute myeloid leukemia 1 protein (AML1) or core-binding factor subunit alpha-2 (CBFA2) is a...

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Transcription factor

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In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic...

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CBFB

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Core-binding factor subunit beta is a protein that in humans is encoded by the CBFB gene. The protein encoded by this gene is the beta subunit of a heterodimeric...

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CAAT box

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initial transcription site. The CAAT box signals the binding site for the RNA transcription factor, and is typically accompanied by a conserved consensus...

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RUNX2

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Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the...

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Nucleolus

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(upstream activating factor), TBP (TATA-box binding protein), and core binding factor (CBF), which bind promoter elements and form the preinitiation complex...

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Runt domain

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myeloid leukemia 1 protein, oncogene AML-1, core-binding factor (CBF), alpha-B subunit, etc.) binds to the core site, 5'-pygpyggt-3', of a number of enhancers...

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CBF

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beat frequency; see Cilium Core binding factor, a type of transcription factor C-Repeat Binding Factor, transcription factors in plants Brazilian Football...

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Sigma factor

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initiation factor that enables specific binding of RNA polymerase (RNAP) to gene promoters. It is homologous to archaeal transcription factor B and to eukaryotic...

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CBFA2T3

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Protein CBFA2T3 (core-binding factor, runt domain, alpha subunit 2; translocated to, 3) is a protein that in humans is encoded by the CBFA2T3 gene. The...

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Transcription factor II D

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composed of TBP and several subunits called TATA-binding protein Associated Factors (TBP-associated factors, or TAFs). In a test tube, only TBP is necessary...

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Transcription factor II B

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formation by binding and stabilising the DNA-TBP (TATA-binding protein) complex and by recruiting RNA polymerase II and other transcription factors. It is encoded...

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Stress granule

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associated with 40S ribosomal subunits, translation initiation factors, poly(A)+ mRNAs and RNA-binding proteins (RBPs). While they are membraneless organelles...

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Pioneer factor

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transcription factors and histone modification enzymes as well as controlling DNA methylation. They were first discovered in 2002 as factors capable of binding to...

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Nucleosome

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non-sequence-specific DNA-binding factor. Although nucleosomes tend to prefer some DNA sequences over others, they are capable of binding practically to any...

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Transcription factor binding site databases

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profiling of DNA-binding proteins and histone modifications. The application of ChIP-seq methods has reliably discovered transcription factor binding sites and...

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TATA box

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TATA-containing genes. The TATA box is the binding site of the TATA-binding protein (TBP) and other transcription factors in some eukaryotic genes. Gene transcription...

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RUNX3

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Runx3 in this tissue. RUNX3 has been shown to interact with TLE1. Core binding factor RUNX1 RUNX2 GRCh38: Ensembl release 89: ENSG00000020633 – Ensembl...

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Bacterial DNA binding protein

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structuring H-NS protein. DNA-binding domain DNA-binding protein DNA-binding protein from starved cells Transcription factor Drlica K, Rouviere-Yaniv J (September...

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Transcriptional regulation

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particular transcription factor that is important for regulation of methylation of CpG islands. An EGR1 transcription factor binding site is frequently located...

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