Transcription factor binding site databases information
Transcription factors are proteins that bind genomic regulatory sites. Identification of genomic regulatory elements is essential for understanding the dynamics of developmental, physiological and pathological processes. Recent advances in chromatin immunoprecipitation followed by sequencing (ChIP-seq) have provided powerful ways to identify genome-wide profiling of DNA-binding proteins and histone modifications.[1][2] The application of ChIP-seq methods has reliably discovered transcription factor binding sites and histone modification sites.
^Park PJ (October 2009). "ChIP-seq: advantages and challenges of a maturing technology". Nature Reviews. Genetics. 10 (10): 669–680. doi:10.1038/nrg2641. PMC 3191340. PMID 19736561.
binding sites and histone modification sites. Comprehensive List of transcriptionfactorbindingsites (TFBSs) databases based on ChIP-seq data as follows:...
molecular biology, a transcriptionfactor (TF) (or sequence-specific DNA-bindingfactor) is a protein that controls the rate of transcription of genetic information...
The publications have been cited 144 and 151 times. Transcriptionfactorbindingsitedatabases Vorontsov, Ilya E; Eliseeva, Irina A; Zinkevich, Arsenii;...
secondary metabolism. Like many transcriptionfactors, WRKY transcriptionfactors are defined by the presence of a DNA-binding domain; in this case, it is...
TRANSFAC (TRANScriptionFACtordatabase) is a manually curated database of eukaryotic transcriptionfactors, their genomic bindingsites and DNA binding profiles...
database of manually curated, non-redundant transcriptionfactor (TF) binding profiles stored as position frequency matrices (PFM) and transcription factor...
(transcription). It is accomplished through the sequence-specific binding of proteins (transcriptionfactors) that activate or inhibit transcription....
particular RNA sequence revealed that the binding strength of a small transcriptionfactor (transcriptionfactor IIIA; TFIIIA) was due to the presence of...
regulatory sequences that post-transcriptionally influence gene expression. Such 3'-UTRs often contain both bindingsites for microRNAs (miRNAs) as well...
respiratory factor 1, also known as Nrf1, Nrf-1, NRF1 and NRF-1, encodes a protein that homodimerizes and functions as a transcriptionfactor which activates...
bindingsites of 22 transcriptionfactors. Up to 20% of the annotated candidate genes were assigned to transcriptionfactors. Several transcription factors...
Biological databases are stores of biological information. The journal Nucleic Acids Research regularly publishes special issues on biological databases and...
database. X-ray crystallographic analysis has shown that the E2F family of transcriptionfactors has a fold similar to the winged-helix DNA-binding motif...
Gene Expression Database at the Jackson Laboratory CollecTF: a database of experimentally validated transcriptionfactor-bindingsites in Bacteria. COLOMBOS:...
functionally related to transcriptional activity, since this remodeled state is necessary for the binding of proteins such as transcriptionfactors. Since the discovery...
eukaryotes. Homeobox genes encode homeodomain protein products that are transcriptionfactors sharing a characteristic protein fold structure that binds DNA to...
Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-bindingfactor is a transcriptionfactor that in humans is encoded by the...
Global Information