Chemical compound
Cinaciguat Routes of administration intravenous (?) ATC code
4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl) phenyl]methoxy}phenyl)ethyl]amino}methyl) benzoic acid
CAS Number 329773-35-5 Y PubChem CID IUPHAR/BPS ChemSpider 7983781 N UNII ChEBI CompTox Dashboard (EPA ) DTXSID40954614 Formula C 36 H 39 N O 5 Molar mass 565.710 g·mol−1 3D model (JSmol)
c4ccccc4CCc3ccc(cc3)COc1ccccc1CCN(CCCCC(O)=O)Cc2ccc(C(=O)O)cc2
InChI=1S/C36H39NO5/c38-35(39)12-6-7-24-37(26-30-19-21-33(22-20-30)36(40)41)25-23-32-10-4-5-11-34(32)42-27-31-17-15-29(16-18-31)14-13-28-8-2-1-3-9-28/h1-5,8-11,15-22H,6-7,12-14,23-27H2,(H,38,39)(H,40,41)
N Key:WPYWMXNXEZFMAK-UHFFFAOYSA-N
N
N Y (what is this?) (verify)
Cinaciguat (BAY 58-2667 ) is an experimental drug for the treatment of acute decompensated heart failure.
Last Update: 2023-01-23T11:40:10Z
Cinaciguat (BAY 58-2667) is an experimental drug for the treatment of acute decompensated heart failure. Cinaciguat activates the soluble guanylate cyclase...
Word Count : 75
Last Update: 2024-05-03T14:09:08Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 6742
Last Update: 2024-06-01T02:12:38Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 3501
Last Update: 2024-05-30T04:18:53Z
pathogenesis of PAH. In contrast to NO- and haem-independent sGC activators like cinaciguat , the sGC stimulator riociguat directly stimulates sGC activity independent...
Word Count : 2115
Last Update: 2024-05-24T16:55:04Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 4218
Last Update: 2024-05-31T05:37:07Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 2754
Last Update: 2024-06-03T19:16:28Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 1743
Last Update: 2024-02-26T06:00:26Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 3137
Last Update: 2024-05-21T11:22:54Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 3899
Last Update: 2024-02-07T04:42:51Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 905
Last Update: 2024-03-29T20:19:39Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 1824
Last Update: 2024-05-24T04:09:57Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 1721
Last Update: 2024-02-29T16:11:14Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 505
Last Update: 2024-02-07T04:43:02Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 832
Last Update: 2024-04-27T00:38:00Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 2689
Last Update: 2024-03-08T19:31:55Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 3325
Last Update: 2024-03-29T23:02:52Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 2639
Last Update: 2024-02-18T07:05:16Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 1641
Last Update: 2024-04-25T22:54:06Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 4217
Last Update: 2024-06-02T05:54:37Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 1851
Last Update: 2024-03-03T05:07:53Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 928
Last Update: 2024-05-01T00:01:16Z
intracellular receptor for NO. As of April 2009[update], the sGC activators cinaciguat and riociguat were undergoing clinical trials for the treatment of PAH...
Word Count : 8891
Last Update: 2024-05-13T12:57:51Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 659
Last Update: 2023-12-27T06:39:54Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 1273
Last Update: 2024-04-27T15:42:23Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 1998
Last Update: 2024-06-07T10:33:32Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 607
Last Update: 2024-03-25T04:28:29Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 177
Last Update: 2024-06-03T15:14:09Z
Activators/stimulators: Ataciguat BAY 41-2272 BAY 41-8543 BAY 60-4552 BI-703704 Cinaciguat (BAY 58-2667) GSK-2181236A Praliciguat Riociguat Vericiguat Inhibitors:...
Word Count : 3243