Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Nitroglycerin (NG) (alternative spelling of nitroglycerine), also known as trinitroglycerin (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane, is a dense, colorless, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester. Chemically, the substance is an organic nitrate compound rather than a nitro compound, but the traditional name is retained. Discovered in 1847 by Ascanio Sobrero, nitroglycerin has been used as an active ingredient in the manufacture of explosives, namely dynamite, and as such it is employed in the construction, demolition, and mining industries. It is combined with nitrocellulose to form double-based smokeless powder, which has been used as a propellant in artillery and firearms since the 1880s.
Nitroglycerin has been used for over 130 years in medicine as a potent vasodilator (causing dilation of the vascular system) to treat heart conditions, such as angina pectoris and chronic heart failure. Though it was previously known that these beneficial effects are due to nitroglycerin being converted to nitric oxide, a potent venodilator, the enzyme for this conversion was only discovered to be mitochondrial aldehyde dehydrogenase (ALDH2) in 2002.[4] Nitroglycerin is available in sublingual tablets, sprays, ointments, and patches.[5]
^ ab"Occupational Safety and Health Guideline for Nitroglycerin". Archived from the original on 16 May 2013. Retrieved 19 October 2016.
^NIOSH Pocket Guide to Chemical Hazards. "#0456". National Institute for Occupational Safety and Health (NIOSH).
^"Hazard Rating Information for NFPA Fire Diamonds". Archived from the original on 17 February 2015.
^Chen, Z.; Foster, M. W.; Zhang, J.; Mao, L.; Rockman, H. A.; Kawamoto, T.; Kitagawa, K.; Nakayama, K. I.; Hess, D. T.; Stamler, J. S. (2005). "An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation". Proceedings of the National Academy of Sciences. 102 (34): 12159–12164. Bibcode:2005PNAS..10212159C. doi:10.1073/pnas.0503723102. PMC 1189320. PMID 16103363.
^"Unknown, behind paywall, archived". Archived from the original on 10 May 2017. Retrieved 14 April 2018.
Nitroglycerin (NG) (alternative spelling of nitroglycerine), also known as trinitroglycerin (TNG), nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane...
Dynamite is an explosive made of nitroglycerin, sorbents (such as powdered shells or clay), and stabilizers. It was invented by the Swedish chemist and...
armaments. Nobel's most famous invention, dynamite, was an explosive using nitroglycerin that was patented in 1867. Nobel was later inspired to donate his fortune...
pectoris, a symptom of Ischaemic heart disease, is treated with nitroglycerin. Nitroglycerin is known as a vasodilator. Vasodilators work by relaxing the...
unstable angina or myocardial infarction, lessens with the use of nitroglycerin, but nitroglycerin may also relieve chest pain arising from non-cardiac causes...
angina attacks. Long-acting nitroglycerins such as isosorbide dinitrate or intermittent use of short-acting nitroglycerin (to treat acute symptoms) may...
accommodation for a long period of time. Animal studies have found nitroglycerin, a vasodilator used to treat angina, relaxes the ciliary muscle and...
an explosive material may, for example, be chemical energy, such as nitroglycerin or grain dust pressurized gas, such as a gas cylinder, aerosol can,...
propellants. It is a pale yellow oily liquid. It is somewhat similar to nitroglycerin. TEGDN is often used together with trimethylolethane trinitrate (TMETN)...
medications such as antiplatelets (including aspirin), beta blockers, or nitroglycerin may be recommended. Procedures such as percutaneous coronary intervention...
night and get away by car. Glasscock turns out to be an expert with nitroglycerin. Willis talks his brothers into supporting him, telling them that bankers...
to severe pain. Fentanyl is often used for opioid-tolerant patients. Nitroglycerin, also known as glyceryl trinitrate (GTN), a medication used for heart...
speech to the Knights, revealing the soap bars contain an ingredient for nitroglycerin. The vineyard is a cover for the production of the weapon, which will...
are the esters of nitric acid and alcohols. A well-known example is nitroglycerin, which is not a nitro compound, despite its name. Nitrate esters are...
nitrocellulose with nitroglycerin or other liquid organic nitrate explosives added. Stabilizers and other additives are also used. Nitroglycerin reduces smoke...
Nitrocellulose, or cellulose nitrate, an extremely flammable chemical compound Nitroglycerin, or glyceryl trinitrate, an explosive chemical compound Nitromethane...
rest or minimal exertion and usually lasts more than 20 minutes (if nitroglycerin is not administered) Being severe (at least Canadian Cardiovascular...
somewhat resembles. However, quarter stick firecrackers do not contain nitroglycerin as dynamite does, and have far less explosive power. In the United States...
Sildenafil should not be taken by people on nitric oxide donors such as nitroglycerin (glycerin trinitrate), as this may result in a serious drop in blood...
2023-06-27. Magazine, Smithsonian; Eschner, Kat. "The Man Who Invented Nitroglycerin Was Horrified By Dynamite". Smithsonian Magazine. Retrieved 2023-06-27...
which allows him to make explosions from his hands by detonating the nitroglycerin-like substance he sweats; throughout the series, he learns various different...
in 1963 with 13.5 percent nitroglycerin for shotgun field loads. HS6 was introduced in 1963 with 18 percent nitroglycerin for heavy shotgun loads. HS7...
Nitration gives nitroglycerin, an essential ingredient of various explosives such as dynamite, gelignite, and propellants like cordite. Nitroglycerin under the...
Kimbolton School; in 1847 Ascanio Sobrero of Italy discovered nitroglycerin - nitroglycerin is the main component of dynamite; a detonation occurs at supersonic...
wide variety of explosives. The end products include dry ice bombs and nitroglycerin. Construction of the devices described in the book is generally illegal...
form the backbone of DNA molecules. Esters of nitric acid, such as nitroglycerin, are known for their explosive properties. There are compounds in which...
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