Class of functional groups with a –N=O group attached
Structural formula of nitroso group
In organic chemistry, nitroso refers to a functional group in which the nitric oxide (−N=O) group is attached to an organic moiety. As such, various nitroso groups can be categorized as C-nitroso compounds (e.g., nitrosoalkanes; R−N=O), S-nitroso compounds (nitrosothiols; RS−N=O), N-nitroso compounds (e.g., nitrosamines, RN(−R’)−N=O), and O-nitroso compounds (alkyl nitrites; RO−N=O).
chemical structure R2N−N=O, where R is usually an alkyl group. They feature a nitroso group (NO+) bonded to a deprotonated amine. Most nitrosamines are carcinogenic...
possible carcinogens N-nitrosodiethylamine, N-methylnitrosobutyric acid, or N-nitroso-N-methyl-4-aminobutyric acid in the active pharmaceutical ingredient (API)...
converting organic compounds into nitroso derivatives, i.e., compounds containing the R-NO functionality. C-Nitroso compounds, such as nitrosobenzene...
Due to the electronegativity difference between carbon and nitrogen, the nitroso group has a relatively strong -I effect, but not as strong as the nitro...
is both the name of a molecule, and a class of compounds that include a nitroso (R-NO) group and a urea. Examples include: Arabinopyranosyl-N-methyl-N-nitrosourea...
that form N-nitroso compounds. A principal concern about sodium nitrite is Nitrosation/nitrosylation, the formation of carcinogenic nitroso-compounds in...
acyl nitroso species, which are known to decompose via hydrolysis to HNO and acyl acid. Upon photolysis these compounds release the acyl nitroso species...
formation of N-nitroso compounds, which are strong esophageal carcinogens in several animal models. Roussin red methyl ester, a non-alkylating nitroso compound...
Cupferron is jargon for the ammonium salt of the conjugate base derived from N-nitroso-N-phenylhydroxylamine. It once was a common reagent for the complexation...
N-benzyl derivative from methyl anthranilate with nitrous acid to give the N-nitroso derivative. Reduction by means of sodium thiosulfate leads to the transient...
pits exhibit anti-genotoxic effects and reduce DNA damage induced by N-nitroso-N-methylurea. Stripped fruit clusters are used as brooms. Recently, the...
Transition metal nitroso complexes are coordination complexes containing one or more organonitroso ligands (RNO). Organic nitroso compounds bind to metals...
described as the anion, NO−. Prototypes for such compounds are the organic nitroso compounds, such as nitrosobenzene. A complex with a bent NO ligand is...
meats, is controversial, because of a small connection to cancer risk. Nitroso compounds react with primary amines in acidic environments to form nitrosamines...
Diazo compounds can be obtained in an elimination reaction of N-alkyl-N-nitroso compounds, such as in the synthesis of diazomethane from Diazald or MNNG:...
though it is established that this chemical gives rise to cancer-causing nitroso-compounds. Some traditional and artisanal producers avoid nitrites. Nitrites...
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