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Archaeal initiation factors information


Archaeal initiation factors are proteins that are used during the translation step of protein synthesis in archaea. The principal functions these proteins perform include ribosome RNA/mRNA recognition, delivery of the initiator Met-tRNAiMet, methionine bound tRNAi, to the 40s ribosome, and proofreading of the initiation complex.[1]

  1. ^ Hernández, Greco; Jagus, Rosemary (2016-08-10). "Evolution of Translational Initiation: From Archaea to Eukarya". Evolution of the Protein Synthesis Machinery and Its Regulation. Hernández, Greco,, Jagus, Rosemary. Switzerland. pp. 61–79. doi:10.1007/978-3-319-39468-8_4. ISBN 9783319394688. OCLC 956539514.{{cite book}}: CS1 maint: location missing publisher (link)

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Archaeal initiation factors

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Archaeal initiation factors are proteins that are used during the translation step of protein synthesis in archaea. The principal functions these proteins...

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Initiation factor

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In molecular biology, initiation factors are proteins that bind to the small subunit of the ribosome during the initiation of translation, a part of protein...

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Archaea

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(in the Archaebacteria kingdom), but this term has fallen out of use. Archaeal cells have unique properties separating them from the other two domains...

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Sigma factor

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initiation factor that enables specific binding of RNA polymerase (RNAP) to gene promoters. It is homologous to archaeal transcription factor B and to eukaryotic...

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Archaeal transcription

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archaea. Initiation in archaea is governed by TATA-binding protein (TBP), Archaeal transcription factor B (TFB), and Archaeal transcription factor E (TFE)...

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Archaeal transcription factor B

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Archaeal transcription factor B (ATFB or TFB) is a protein family of extrinsic transcription factors that guide the initiation of RNA transcription in...

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Archaeal translation

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seems to resemble eukaryotic translation. Most of the initiation, elongation, and termination factors in archaea have homologs in eukaryotes. Shine-Dalgarno...

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Origin of replication

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than in bacterial or archaeal domains and significantly deviate from the paradigm established for prokaryotic replication initiation. The large genome sizes...

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Elongation factor

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polypeptide. Most common elongation factors in prokaryotes are EF-Tu, EF-Ts, EF-G. Bacteria and eukaryotes use elongation factors that are largely homologous...

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Release factor

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release factor. Eukaryotic and archaeal release factors are named analogously, with the naming changed to "eRF" for "eukaryotic release factor" and vice...

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Transcription factor II B

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transcription factors. It is encoded by the TFIIB gene, and is homologous to archaeal transcription factor B and analogous to bacterial sigma factors. TFIIB...

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RNA polymerase

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abortive transcription. The extent of abortive initiation depends on the presence of transcription factors and the strength of the promoter contacts. The...

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Alpha beta barrel

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structures known for this fold come proteins from the eukaryotic and archaeal initiation factor 6 family, namely the Methanococcus jannaschii aIF6 and Saccharomyces...

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Eukaryotic ribosome

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for complexes of ribosomes and factors involved in translation. After the determination of the first bacterial and archaeal ribosome structures at atomic...

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Kozak consensus sequence

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codons UUG and GUG for some genes. Archaeal transcripts use a mix of SD sequence, Kozak sequence, and leaderless initiation. Haloarchaea are known to have...

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Ribosome

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with the 3′-end of 16S ribosomal RNA, are involved in the initiation of translation. Archaeal ribosomes share the same general dimensions of bacteria ones...

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RNA polymerase II holoenzyme

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bacterial initiation. In bacteria, the sigma factor recognizes and binds to the promoter sequence. In eukaryotes, the transcription factors perform this...

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TATA box

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upstream of the transcription initiation site and about 150 bases upstream of the TATA box. It binds transcription factors (CAAT TF or CTFs) and thereby...

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Prokaryotic large ribosomal subunit

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Nenad (May 2012). "Cryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome Evolution"...

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Transcription preinitiation complex

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Containing All Essential Initiation Factors Binds to the Activation Domain of PAR Leucine Zipper Transcription Factor Thyroid Embryonic Factor". Molecular and...

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Protein synthesis inhibitor

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portal Protein biosynthesis Bacterial translation Eukaryotic translation Archaeal translation Frank Lowy. "Protein Synthesis Inhibitors" (PDF). Columbia...

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Histone fold

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peptide chains can be found in the archaeal histones, which could have come from eukaryotic H3-H4 tetramer. The archaeal single-chain histones are also found...

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Intrinsic termination

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a hairpin. Archaeal transcription shares eukaryotic and bacterial ties. With eukaryotes, it shares similarities with its initiation factors that help transcription...

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