Transmission electron micrograph of Rubella virus virions
Virus classification
(unranked):
Virus
Realm:
Riboviria
Kingdom:
Orthornavirae
Phylum:
Kitrinoviricota
Class:
Alsuviricetes
Order:
Hepelivirales
Family:
Matonaviridae
Genus:
Rubivirus
Species:
Rubivirus rubellae
Synonyms[1]
Rubella virus
Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.
Rubella virus, scientific name Rubivirus rubellae, is a member of the genus Rubivirus and belongs to the family of Matonaviridae, whose members commonly have a genome of single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid.
As of 1999[update] the molecular basis for the causation of congenital rubella syndrome was not yet completely clear, but in vitro studies with cell lines showed that rubella virus has an apoptotic effect on certain cell types. There is evidence for a p53-dependent mechanism.[2]
^Bennett AJ, Paskey AC, Ebinger A, Kuhn JH, Bishop-Lilly KA, Beer M, Goldberg TL (31 July 2020). "Create two new species and rename one species in genus Rubivirus (Hepelivirales: Matonaviridae)" (docx). International Committee on Taxonomy of Viruses (ICTV). Archived from the original on 21 December 2022. Retrieved 15 May 2021.
^Megyeri K, Berencsi K, Halazonetis TD, et al. (June 1999). "Involvement of a p53-dependent pathway in rubella virus-induced apoptosis". Virology. 259 (1): 74–84. doi:10.1006/viro.1999.9757. PMID 10364491.
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