16-month-old with erythema infectiosum, displaying characteristic red rashes
Specialty
Infectious disease
Symptoms
Red rash, especially on cheeks and harsh coughs
Causes
Human parvovirus
Erythema infectiosum, fifth disease, or slapped cheek syndrome[3] is one of several possible manifestations of infection by parvovirus B19.[4] Fifth disease typically presents as a rash and is more common in children. While parvovirus B19 can affect humans of all ages, only two out of ten individuals will present with physical symptoms.[5]
The name "fifth disease" comes from its place on the standard list of rash-causing childhood diseases, which also includes measles (first), scarlet fever (second), rubella (third), Dukes' disease (fourth, but is no longer widely accepted as distinct from scarlet fever), and roseola (sixth).[6] Treatment is mostly supportive.
^Cite error: The named reference Sabella1999 was invoked but never defined (see the help page).
^Cite error: The named reference Servey2007 was invoked but never defined (see the help page).
^Weir E (March 2005). "Parvovirus B19 infection: fifth disease and more". CMAJ. 172 (6): 743. doi:10.1503/cmaj.045293. PMC 552884. PMID 15767606.
^"About Human Parvovirus B19 | CDC". www.cdc.gov. 2021-04-01. Retrieved 2021-08-04.
^Feder, Henry M.; Grant-Kels, Jane M. (2008), Schlossberg, David (ed.), "Classic Viral Exanthems", Clinical Infectious Disease, Cambridge: Cambridge University Press, pp. 135–140, doi:10.1017/cbo9780511722240.020, ISBN 978-0-511-72224-0, retrieved 2022-01-04
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