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Herpes simplex virus information


Herpes simplex viruses
TEM micrograph of virions of a herpes simplex virus species
TEM micrograph of virions of a herpes simplex virus species
Scientific classificationEdit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Orthoherpesviridae
Subfamily: Alphaherpesvirinae
Genus: Simplexvirus
Groups included
  • Human alphaherpesvirus 1
  • Human alphaherpesvirus 2
Cladistically included but traditionally excluded taxa

All other Simplexvirus spp.:

  • Ateline alphaherpesvirus 1
  • Bovine alphaherpesvirus 2
  • Cercopithecine alphaherpesvirus 2
  • Leporid alphaherpesvirus 4
  • Macacine alphaherpesvirus 1
  • Macropodid alphaherpesvirus 1
  • Macropodid alphaherpesvirus 2
  • Panine alphaherpesvirus 3
  • Papiine alphaherpesvirus 2
  • Pteropodid alphaherpesvirus 1
  • Saimiriine alphaherpesrus 1

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomic names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans.[1][2] Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus.

As of 2016, about 67% of the world population under the age of 50 had HSV-1.[3] In the United States, about 47.8% and 11.9% are estimated to have HSV-1 and HSV-2, respectively, though actual prevalence may be much higher.[4] Because it can be transmitted through any intimate contact, it is one of the most common sexually transmitted infections.[5]

  1. ^ Ryan KJ, Ray CG, eds. (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 555–62. ISBN 978-0-8385-8529-0.
  2. ^ Chayavichitsilp P, Buckwalter JV, Krakowski AC, Friedlander SF (April 2009). "Herpes simplex". Pediatr Rev. 30 (4): 119–29, quiz 130. doi:10.1542/pir.30-4-119. PMID 19339385. S2CID 34735917.
  3. ^ "Herpes simplex virus". World Health Organization. 31 January 2017.
  4. ^ "Prevalence of Herpes Simplex Virus Type 1 and 2" (PDF). CDC NCHS Data Brief. 16 February 2020.
  5. ^ Straface G, Selmin A, Zanardo V, De Santis M, Ercoli A, Scambia G (2012). "Herpes simplex virus infection in pregnancy". Infectious Diseases in Obstetrics and Gynecology. 2012: 385697. doi:10.1155/2012/385697. PMC 3332182. PMID 22566740.

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variety of symptoms. Similar to the herpes simplex viruses, after primary infection with VZV (chickenpox), the virus lies dormant in neurons, including...

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the signs and symptoms presented. Varicella zoster virus is not the same as herpes simplex virus, although they belong to the same family of herpesviruses...

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flares of herpes simplex 1, herpes simplex 2 and herpes zoster (shingles). In 1971, the International Committee on the Taxonomy of Viruses (ICTV) established...

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A herpetic whitlow is a herpes lesion (whitlow), typically on a finger or thumb, caused by the herpes simplex virus (HSV). Occasionally infection occurs...

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the herpes virus family, Herpesviridae, all of which establish latent infection. Herpes virus include chicken-pox virus and herpes simplex viruses (HSV-1...

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in humans Herpes simplex virus 1 and 2, responsible for herpes simplex infections Human alphaherpesvirus 3, also called varicella-zoster virus, responsible...

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Human alphaherpesvirus 2

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Human alphaherpesvirus 2 or Herpes simplex virus 2 (HHV-2 or HSV-2) is a species of virus in the genus Simplexvirus, subfamily Alphaherpesvirinae, family...

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Herpes esophagitis is a viral infection of the esophagus caused by Herpes simplex virus (HSV). While the disease most often occurs in immunocompromised...

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Oncolytic virus

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begin until the 1960s. A number of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus, and vaccinia have been clinically...

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Arginine

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growth hormone. Research from 1964 into amino acid requirements of herpes simplex virus in human cells indicated that "...the lack of arginine or histidine...

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Eczema herpeticum

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to human herpes simplex virus, and the term "Kaposi varicelliform eruption" to describe the general presentation without specifying the virus. This condition...

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Herpes simplex virus protein vmw65

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Oct-1 and HCF to induce immediate early gene transcription in the herpes simplex viruses. VP16 is a strong transactivator and is often used in Y2H systems...

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Viral encephalitis

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Aciclovir

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antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention...

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neurotropic viruses are highly neuroinvasive for the peripheral nervous system (e.g. herpes simplex virus). Important neuroinvasive viruses include poliovirus...

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