Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Phalloidin belongs to a class of toxins called phallotoxins, which are found in the death cap mushroom (Amanita phalloides). It is a rigid bicyclic heptapeptide that is lethal after a few days when injected into the bloodstream. The major symptom of phalloidin poisoning is acute hunger due to the destruction of liver cells. It functions by binding and stabilizing filamentous actin (F-actin) and effectively prevents the depolymerization of actin fibers. Due to its tight and selective binding to F-actin, derivatives of phalloidin containing fluorescent tags are used widely in microscopy to visualize F-actin in biomedical research.
Phalloidin belongs to a class of toxins called phallotoxins, which are found in the death cap mushroom (Amanita phalloides). It is a rigid bicyclic heptapeptide...
residue smaller, both in the final product and the precursor protein. Phalloidin had been isolated in 1937 by Feodor Lynen, Heinrich Wieland's student...
fluorescent reporter. A major example of this class of fluorescent stain is phalloidin, which is used to stain actin fibers in mammalian cells. A new peptide...
of the cytoskeleton, such as taxol, which stabilizes microtubules, or Phalloidin, which stabilizes actin filaments. Others, such as Cytochalasin D, bind...
These filaments have been visualized at high resolution using fluorescent phalloidin that binds to actin filaments. The stereocilia in the epididymis are non-motile...
least seven compounds, all of which have seven similar peptide rings. Phalloidin was isolated in 1937 by Feodor Lynen, Heinrich Wieland's student and son-in-law...
structure has not been determined. Amanitin is very closely related to phalloidins, which are bicyclic 7-residue toxins. They both are part of the MSDIN...
least seven compounds, all of which have seven similar peptide rings. Phalloidin was isolated in 1937 by Feodor Lynen, Heinrich Wieland's student and son-in-law...
It is being studied as a potential anti-toxin against the effects of phalloidin and for its potential for treating edema. It contains 1 valine residue...
is found in the toxic cyclic peptides from Amanita mushrooms (e.g., phalloidin). Secondary amino acid Imino acid Hydroxylysine R.H.A. Plimmer (1912)...
the HIV envelope sequence required for attachment to the CD4 receptor. Phalloidin - A very toxic polypeptide isolated mainly from Amanita phalloides (Agaricaceae)...
fluorescence image of HeLa cells stained with the actin- binding toxin phalloidin (red), microtubules (cyan), and cell nuclei (blue). Nikon RTS2000MP custom...
can be observed under the microscope thanks to fluorophore-conjugated phalloidin staining. In somatic cell nuclei, however, actin filaments cannot be observed...
free-floating DDY mouse jejunum (green: phospho-Girdin at tyrosine 1798, red: phalloidin, blue: DAPI) prepared by Iida M, Tanaka M, Asai M in Institute for Developmental...
mitochondria stained red with MitoTracker Red CMXRos, and F-actin stained green with Alexa Fluor 488 phalloidin and imaged on a fluorescent microscope....
tobacco leaves are treated with a drug that stabilizes actin filaments, phalloidin, the cucumber mosaic virus movement proteins are unable to increase the...
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