Scanning electron micrograph of an apoptotic HeLa cell. Zeiss Merlin HR-SEM.Multiphoton fluorescence image of cultured HeLa cells with a fluorescent protein targeted to the Golgi apparatus (orange), microtubules (green) and counterstained for DNA (cyan). Nikon RTS2000MP custom laser scanning microscope.Immunofluorescence image of HeLa cells grown in tissue culture and stained with antibody to actin in green, vimentin in red and DNA in blueImmunofluorescence of HeLa cells showing microtubules in green, mitochondria in yellow, nucleoli in red and nuclear DNA in purple
HeLa (/ˈhiːlɑː/) is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used.[1][2] HeLa cells are durable and prolific, allowing for extensive applications in scientific study.[3][4] The line is derived from cervical cancer cells taken on 8 February 1951,[5] from Henrietta Lacks, a 31-year-old African American mother of five, after whom the line is named. Lacks died of cancer on 4 October 1951.[6]
The cells from Lacks's cancerous cervical tumor were taken without her knowledge, which was common practice in the United States at the time.[7] Cell biologist George Otto Gey found that they could be kept alive,[8] and developed a cell line. Previously, cells cultured from other human cells would survive for only a few days, but cells from Lacks's tumor behaved differently.
^Rahbari R, Sheahan T, Modes V, Collier P, Macfarlane C, Badge RM (2009). "A novel L1 retrotransposon marker for HeLa cell line identification". BioTechniques. 46 (4): 277–284. doi:10.2144/000113089. PMC 2696096. PMID 19450234.
^Morris, Rhys Bowen (August 2, 2023). "What were the top 100 cell lines of 2022?". CiteAb Blog. Retrieved August 17, 2023.
^Capes-Davis A, Theodosopoulos G, Atkin I, Drexler HG, Kohara A, MacLeod RA, Masters JR, Nakamura Y, Reid YA, Reddel RR, Freshney RI (2010). "Check your cultures! A list of cross-contaminated or misidentified cell lines". Int. J. Cancer. 127 (1): 1–8. doi:10.1002/ijc.25242. PMID 20143388. S2CID 2929020.
^Batts DW (May 10, 2010). "Cancer cells killed Henrietta Lacks – then made her immortal". The Virginian-Pilot. pp. 1, 12–14. Archived from the original on November 25, 2016. Retrieved May 8, 2020.
^Scherer, W.F.; Syverton, J.T.; Gey, G.O. (1953). "Studies on the propagation in vitro of poliomyelitis viruses. IV. Viral multiplication in a stable strain of human malignant epithelial cells (strain HeLa) derived from an epidermoid carcinoma of the cervix". Journal of Experimental Medicine. 97 (5): 695–710. doi:10.1084/jem.97.5.695. PMC 2136303. PMID 13052828.
^"Johns Hopkins Magazine -- April 2000". pages.jh.edu.
^Ron Claiborne; Sydney Wright, IV (January 31, 2010). "How One Woman's Cells Changed Medicine". ABC World News. Retrieved August 19, 2012.
^McKie, Robin (April 3, 2010). "Henrietta Lacks's cells were priceless, but her family can't afford a hospital". The Guardian. London. Retrieved July 18, 2017.
HeLa (/ˈhiːlɑː/) is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. HeLa cells...
Southern Highlands Province of Papua New Guinea Hela, the German name for Hel, Poland 699 Hela, an asteroid HeLa, a line of cells derived from deceased American...
compensated for the extraction or use of the HeLa cells. Even though some information about the origins of HeLa's immortalized cell lines was known to researchers...
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caspase-3. However, apoptosis induced by CDV in HeLa cells does not involve the initiator protein caspase-8. HeLa cell apoptosis caused by CDV follows a different...
origins of some immortal cell lines, for example HeLa human cells, are from naturally occurring cancers. HeLa, the first immortal human cell line on record...
HelaHela Pass, also known as Helehele Pass, is situated in the KwaZulu-Natal province of South Africa, on the road between Richmond and Donnybrook. Access...
Lacks Health and Bioscience High School, commonly known as HeLa (alternatively spelled He-La), is a high school located in Vancouver, Washington. It is...
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The Jathika Hela Urumaya (abbrv. JHU; Sinhala: ජාතික හෙළ උරුමය; Tamil: ஈழ மக்கள் கழகம்), less commonly known by its English name the National Heritage...
Kyrie Andrew Irving (/ˈkaɪri/ KY-ree; Lakota: Ȟéla, lit. 'Little Mountain'; born March 23, 1992) is an American professional basketball player for the...
The book is about Henrietta Lacks and the immortal cell line, known as HeLa, that came from Lacks's cervical cancer cells in 1951. Skloot became interested...
Hela Yungst Hochman (January 15, 1950 - February 24, 2002), also known as Hela Young, was an American television entertainer and beauty pageant winner...
characteristics (e.g., by mutation or viral transfection, for example the HeLa derivate Det98) and thus constitute a novel lineage after all, so are not...
cell line. For example, HeLa CCL-2 is a common cell line used in a wide variety of research areas. To test the purity of the HeLa cells, CPEs were observed...
Hospital who is credited with propagating the HeLa cell line from Henrietta Lacks' cervical tumor. He spent over 35 years developing numerous scientific...
Heikki Hela (born 19 July 1964 in Aitolahti) is a Finnish entertainer, actor and musician, best remembered for his role in the early 1990s hit show Kummeli...
699 Hela is a Mars crossing asteroid. It was discovered on 5 June 1910 at Heidelberg by German astronomer Joseph Helffrich, and may have been named after...
of chromosomes in animal cells. In 1953, a lab mistake involving mixing HeLa cells with the wrong liquid led Joe Hin Tjio and Albert Levan to develop...
The Kroton Hela Wigmen is a semi-professional Papua New Guinean rugby league team from Hela Province. They currently compete in the Papua New Guinea National...
"Fest i hela huset" (transl. "Party in the house") is a song by Swedish musician Basshunter, recorded during the fifth season of the Swedish edition of...
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