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Pancreatic polypeptide information


Pancreatic polypeptide
Identifiers
SymbolPPY
NCBI gene5539
HGNC9327
OMIM167780
RefSeqNM_002722
UniProtP01298
Other data
LocusChr. 17 p11.1-qter
Search for
StructuresSwiss-model
DomainsInterPro
Immunohistochemistry for pancreatic polypeptide in a mouse pancreas, 200×

Pancreatic polypeptide (PP) is a polypeptide secreted by PP cells in the endocrine pancreas. It regulates pancreatic secretion activities, and also impacts liver glycogen storage and gastrointestinal secretion. Its secretion may be impacted by certain endocrine tumours.

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Pancreatic polypeptide

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Pancreatic polypeptide (PP) is a polypeptide secreted by PP cells in the endocrine pancreas. It regulates pancreatic secretion activities, and also impacts...

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Pancreatic polypeptide cells

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Pancreatic polypeptide cells (PP cells), or formerly as gamma cells (γ-cells), or F cells, are cells in the pancreatic islets (Islets of Langerhans) of...

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Pancreas

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somatostatin and pancreatic polypeptide. As a part of the digestive system, it functions as an exocrine gland secreting pancreatic juice into the duodenum...

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Peptide

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NPY (NeuroPeptide Y) PYY (Peptide YY) APP (Avian Pancreatic Polypeptide) PPY Pancreatic PolYpeptide Proopiomelanocortin (POMC) peptides Enkephalin pentapeptides...

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Pancreatic islets

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insulin and amylin (≈70%) PP cells (gamma cells or F cells) producing pancreatic polypeptide (<5%) Delta cells producing somatostatin (<10%) Epsilon cells producing...

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Pancreatic neuroendocrine tumor

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there is no secretion, or the quantity or type of products, such as pancreatic polypeptide (PPoma), chromogranin A, and neurotensin, do not cause a clinical...

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Amylin

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Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio of...

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Gastric inhibitory polypeptide

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Gastric inhibitory polypeptide (GIP), also known as glucose-dependent insulinotropic polypeptide, is an inhibiting hormone of the secretin family of hormones...

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Pancreatic polypeptide receptor 1

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Pancreatic polypeptide receptor 1, also known as Neuropeptide Y receptor type 4, is a protein that in humans is encoded by the PPYR1 gene. Pancreatic...

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PP

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an antipsychotic medication Pancreatic polypeptide, a polypeptide secreted by PP cells PP cell or pancreatic polypeptide cell pro parte, abbreviated p...

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Endocrine system

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and pancreatic polypeptide. During the early stages of fetal development, the number of pancreatic alpha cells outnumbers the number of pancreatic beta...

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Peptide YY

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YY3-36 (PYY) is a linear polypeptide consisting of 34 amino acids with structural homology to NPY and pancreatic polypeptide. The PP-fold motif is found...

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Peptide hormone

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Cholecystokinin (CCK) Gastrin Ghrelin Glucagon Glucose-dependent insulinotropic polypeptide (GIP) Glucagon-like peptide-1 (GLP-1) Growth hormone Follicle-stimulating...

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Neuroendocrine tumor

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either don't secrete, or the quantity or type of products such as pancreatic polypeptide (PPoma), chromogranin A, and neurotensin do not cause a clinical...

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Motilin

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sphincter. Other functions of motilin include increasing the release of pancreatic polypeptide and somatostatin. Erythromycin and related antibiotics act as non-peptide...

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Vitamin D

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PTH Gonadal axis Pancreas Glucagon Insulin Amylin Somatostatin Pancreatic polypeptide Pineal gland Melatonin N,N-Dimethyltryptamine 5-Methoxy-N,N-dimethyltryptamine...

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Calcitonin

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other gastrointestinal disorders, and pulmonary disease. Calcitonin is a polypeptide hormone of 32 amino acids, with a molecular weight of 3454.93 daltons...

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Proglucagon

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preproglucagon to form proglucagon Glicentin (21–89) Glicentin-related pancreatic polypeptide (GRPP, 21-50) Oxyntomodulin (OXY or OXM, 53–89) Glucagon (53–81)...

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Glossary of diabetes

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glucagon; delta cells, which make somatostatin; F cells which make pancreatic polypeptide, and D1 cells, about which little is known. The names of the cell...

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Type 3c diabetes

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known as pancreatogenic diabetes) is diabetes that comes secondary to pancreatic diseases, involving the exocrine and digestive functions of the pancreas...

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Epidermal growth factor

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EGF has been found to be stimulated by testosterone.[citation needed] Polypeptide growth factors include: EGF acts by binding with high affinity to epidermal...

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Adrenocorticotropic hormone

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Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland...

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Glucagon

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belongs to the secretin family of hormones. Glucagon is a 29-amino acid polypeptide. Its primary structure in humans is: NH2-His-Ser-Gln-Gly-Thr-Phe-Thr...

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Vasoactive intestinal peptide

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Vasoactive intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine. VIP is...

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List of human hormones

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vasoconstriction, Platelet Aggregation 11 Amylin (or Islet Amyloid Polypeptide) IAPP Peptide pancreas pancreatic β-cells amylin receptor slowing down gastric emptying...

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Atrial natriuretic peptide

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translation of this gene yielding a high molecular mass 151 amino acid polypeptide known as preproANP. The preprohormone is activated via post-translational...

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Nerve growth factor

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involving NGF have been identified, two of them being the survival of pancreatic beta cells and the regulation of the immune system. NGF is initially in...

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Enteroendocrine cell

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opposite effect. Other hormones produced include somatostatin, pancreatic polypeptide, amylin and ghrelin. Rare and slow growing carcinoid and non-carcinoid...

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Melatonin

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PTH Gonadal axis Pancreas Glucagon Insulin Amylin Somatostatin Pancreatic polypeptide Pineal gland Melatonin N,N-Dimethyltryptamine 5-Methoxy-N,N-dimethyltryptamine...

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Growth hormone

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receptors on certain types of cells. GH is a 191-amino acid, single-chain polypeptide that is synthesized, stored and secreted by somatotropic cells within...

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