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Mature messenger RNA information


Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation in the course of protein synthesis. Unlike the eukaryotic RNA immediately after transcription known as precursor messenger RNA,[1] mature mRNA consists exclusively of exons and has all introns removed.

The Maturation of mRNA

Mature mRNA is also called "mature transcript", "mature RNA" or "mRNA".

The production of a mature mRNA molecule occurs in 3 steps:[2][3]

  1. Capping of the 5' end
  2. Polyadenylation of the 3' end
  3. RNA Splicing of the introns
  1. ^ Alberts, Bruce (2015). Molecular biology of the cell (Sixth ed.). Abingdon, UK: Garland Science, Taylor and Francis Group. ISBN 978-0815344643.
  2. ^ O'Connor, Clare (2010). Essentials of Cell Biology. NPG Education: Cambridge, MA. Retrieved November 11, 2021.
  3. ^ Toole, Glenn; Toole, Susan (2015). AQA biology A level. Student book (Second ed.). Great Clarendon Street, Oxford, OX2 6DP, UK: Oxford University Press. ISBN 9780198351771.{{cite book}}: CS1 maint: location (link)

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Mature messenger RNA

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Mature messenger RNA, often abbreviated as mature mRNA is a eukaryotic RNA transcript that has been spliced and processed and is ready for translation...

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Primary transcript

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nuclear RNA (hnRNA). Once pre-mRNA has been completely processed, it is termed "mature messenger RNA", or simply "messenger RNA". The term hnRNA is often...

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RNA splicing

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RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger...

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Messenger RNA

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In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is...

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Genomic DNA

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in the mature messenger RNA (mRNA). Additional processing includes the addition of a 5' cap and a poly(A) tail to the pre-mRNA. The mature mRNA may then...

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Splice site mutation

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splicing takes place during the processing of precursor messenger RNA into mature messenger RNA. Splice site consensus sequences that drive exon recognition...

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Transfer RNA

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codon in a messenger RNA (mRNA) by a 3-nucleotide anticodon of the tRNA results in protein synthesis based on the mRNA code. As such, tRNAs are a necessary...

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MicroRNA

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refers to the mature form of the miRNA, while the uncapitalized "mir-" refers to the pre-miRNA and the pri-miRNA. The genes encoding miRNAs are also named...

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Gene

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repressor proteins and make the DNA less available for RNA polymerase. The mature messenger RNA produced from protein-coding genes contains untranslated...

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RNA

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(non-coding RNA) or by forming a template for the production of proteins (messenger RNA). RNA and deoxyribonucleic acid (DNA) are nucleic acids. The nucleic acids...

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Ribosomal RNA

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transfer RNA (tRNA) and messenger RNA (mRNA) to process and translate the latter into proteins. Ribosomal RNA is the predominant form of RNA found in...

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Polyadenylation

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Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine monophosphates;...

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Coding region

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within the exons, which become covalently joined together to form the mature messenger RNA. Mutations in the coding region can have very diverse effects on...

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RNA polymerase

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nucleotides. RNAP produces RNA that, functionally, is either for protein coding, i.e. messenger RNA (mRNA); or non-coding (so-called "RNA genes"). Examples of...

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Circular RNA

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transcribed from DNA into a messenger RNA (mRNA) transcript, intervening introns are removed, leaving only exons in the mature mRNA, which can subsequently...

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Silent mutation

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introns out of the mRNA sequence leading to the wrong exons being produced. Therefore, making a change to the mature messenger RNA. Mutations in the Multi-Drug...

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Small nuclear RNA

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processing of pre-messenger RNA (hnRNA) in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase...

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Gene expression

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"zipcodes") on the RNA. For some non-coding RNA, the mature RNA is the final gene product. In the case of messenger RNA (mRNA) the RNA is an information...

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Protein biosynthesis

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called messenger RNA (mRNA). This conversion is carried out by enzymes, known as RNA polymerases, in the nucleus of the cell. In eukaryotes, this mRNA is...

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History of RNA biology

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repetitive folded structure of the DNA double helix. Analysis of mature eukaryotic messenger RNA molecules showed that they are often much smaller than the...

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FET protein family

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gene family which encode them (i.e. form the pre-messenger RNAs that are converted to the messenger RNAs responsible for their production) are: 1) the EWSR1...

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HIV

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U5:AUG regions of the gRNA participate in extensive base pairing. RNA can also be processed to produce mature messenger RNAs (mRNAs). In most cases, this...

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Baltimore classification

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viruses based on their manner of messenger RNA (mRNA) synthesis. By organizing viruses based on their manner of mRNA production, it is possible to study...

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