Transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA[1]) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length (in eukaryotes),[2] that serves as the physical link between the mRNA and the amino acid sequence of proteins. Transfer RNA (tRNA) does this by carrying an amino acid to the protein-synthesizing machinery of a cell called the ribosome. Complementation of a 3-nucleotide codon in a messenger RNA (mRNA) by a 3-nucleotide anticodon of the tRNA results in protein synthesis based on the mRNA code. As such, tRNAs are a necessary component of translation, the biological synthesis of new proteins in accordance with the genetic code.
^Plescia OJ, Palczuk NC, Cora-Figueroa E, Mukherjee A, Braun W (October 1965). "Production of antibodies to soluble RNA (sRNA)". Proceedings of the National Academy of Sciences of the United States of America. 54 (4): 1281–1285. Bibcode:1965PNAS...54.1281P. doi:10.1073/pnas.54.4.1281. PMC 219862. PMID 5219832.
^Sharp SJ, Schaack J, Cooley L, Burke DJ, Söll D (1985). "Structure and transcription of eukaryotic tRNA genes". CRC Critical Reviews in Biochemistry. 19 (2): 107–144. doi:10.3109/10409238509082541. PMID 3905254.
TransferRNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides...
forces transferRNA (tRNA) and messenger RNA (mRNA) to process and translate the latter into proteins. Ribosomal RNA is the predominant form of RNA found...
three universal types of RNA include transferRNA (tRNA), messenger RNA (mRNA), and ribosomal RNA (rRNA). Messenger RNA acts to carry genetic sequence information...
the ribosome creates the protein utilizing amino acids carried by transferRNA (tRNA). This process is known as translation. All of these processes form...
ribosomal RNAs (12S and 16S), and 14 transferRNAs (tRNAs). The light strand encodes one subunit, and 8 tRNAs. So, altogether mtDNA encodes for two rRNAs, 22...
(so-called "RNA genes"). Examples of four functional types of RNA genes are: TransferRNA (tRNA) Transfers specific amino acids to growing polypeptide chains at...
known as aminoacylation or tRNA charging) refers to the attachment of an amino acid to its respective transferRNA (tRNA). The reaction occurs in the...
also some non-coding RNAs (e.g., snRNAs, snoRNAs or long non-coding RNAs). RNA polymerase III transcribes 5S rRNA, transferRNA (tRNA) genes, and some small...
aminoacylated transferRNAs (tRNAs) into the ribosome-mRNA complex, matching the codon in the mRNA to the anti-codon on the tRNA. Each tRNA bears the appropriate...
well as stability of RNAs, and has been linked with human diseases. RNA editing has been observed in some tRNA, rRNA, mRNA, or miRNA molecules of eukaryotes...
researchers reported evidence suggesting that a preliminary form of transferRNA, a necessary component of translation, the biological synthesis of new...
termed soluble (sRNA) and were later renamed transferRNA (tRNA). Subsequent studies showed that (i) every cell has multiple species of tRNA, each of which...
RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger...
single-stranded nucleic acids. This is particularly important in RNA molecules (e.g., transferRNA), where Watson–Crick base pairs (guanine–cytosine and adenine–uracil)...
order specified by messenger RNA (mRNA), using transferRNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The...
processing reactions, including RNA splicing, viral replication, and transferRNA biosynthesis. Examples of ribozymes include the hammerhead ribozyme,...
protein. Other types of RNA include ribosomal RNA (rRNA) and transferRNA (tRNA). These types are transcribed by RNA polymerase I and RNA polymerase III, respectively...
encodes a protein (if it is an mRNA) or forms a 'structural' RNA, such as a transferRNA (tRNA) or ribosomal RNA (rRNA) molecule. Each region of the DNA...
dogma, as transfers of information from RNA to DNA are explicitly held possible. Retroviral RT has three sequential biochemical activities: RNA-dependent...
The D arm is a feature in the tertiary structure of transferRNA (tRNA). It is composed of the two D stems and the D loop. The D loop contains the base...
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