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MST1 information


MST1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMST1, D3F15S2, DNF15S2, HGFL, MSP, NF15S2, macrophage stimulating 1
External IDsOMIM: 142408 MGI: 96080 HomoloGene: 7360 GeneCards: MST1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_008243

RefSeq (protein)

NP_066278

NP_032269

Location (UCSC)Chr 3: 49.68 – 49.69 MbChr 9: 107.96 – 107.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded by the MST1 (macrophage-stimulating 1) gene.[5][6][7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000173531 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032591 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gerber MJ, Drabkin HA, Firnhaber C, Miller YE, Scoggin CH, Smith DI (Oct 1988). "Regional localization of chromosome 3-specific DNA fragments by using a hybrid cell deletion mapping panel". Am J Hum Genet. 43 (4): 442–51. PMC 1715492. PMID 2902784.
  6. ^ Yoshimura T, Yuhki N, Wang MH, Skeel A, Leonard EJ (Aug 1993). "Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3". J Biol Chem. 268 (21): 15461–8. doi:10.1016/S0021-9258(18)82279-7. PMID 8393443.
  7. ^ "Entrez Gene: MST1 macrophage stimulating 1 (hepatocyte growth factor-like)".

and 24 Related for: MST1 information

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MST1

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protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded by the MST1 (macrophage-stimulating 1) gene. GRCh38: Ensembl release 89: ENSG00000173531...

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Hippo signaling pathway

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which Hpo phosphorylates (Drosophila) the protein kinase Warts (Wts). Hpo (MST1/2 in mammals) is a member of the Ste-20 family of protein kinases. This highly...

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Rap1

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knockdown of Mst1 expression. Although Rap1 and RAPL have been shown to regulate both LFA-1 affinity and clustering, overexpression of Mst1 only enhances...

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YAP1

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phosphorylate Ste20-like kinases, MST1/2, at their activation loops (Thr183 for MST1 and Thr180 for MST2). Active MST1/2 then phosphorylate SAV1 and MOB1A/B...

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P53

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Figeys D, et al. (December 2002). "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis". The Journal of Biological Chemistry. 277 (50):...

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Contact inhibition

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binding to growth-controlling genes. The serine/threonine kinase Hippo (Mst1/Mst2 encoded by the STK4 and STK3 genes respectively in mammals) activates...

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STK3

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MST2, as well as lower kinase activity compared to both MST2/MST2 and MST1/MST1 homodimers. In addition to activation by straurosporine and FAS ligand...

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STK4

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D, Avruch J (December 2002). "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis". J. Biol. Chem. 277 (50): 47991–8001. doi:10...

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MST

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MST3K), an American television comedy series. Macrophage-stimulating 1 (MST1), gene encoding the macrophage-stimulating protein This disambiguation page...

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Panchvati Express

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12109 : MUMBAI CST->MANMAD Engine-EOG-GEN1-GEN2-GEN3-GEN4-GEN5-GEN6-GEN7-GEN8-MST1-MST2-D5-D4-D3-D2-D1-C1-C2-C3(AC MST)-LDS-EOG.; Total Coaches-21 12110 : MANMAD->MUMBAI...

Word Count : 412

PRKRIR

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Daniel; Avruch Joseph (Dec 2002). "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis". J. Biol. Chem. 277 (50). United States: 47991–8001...

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List of human clusters of differentiation

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(AML). CD136 Macrophage-stimulating protein receptor, (MST1R gene); binds to MST1 ligand; CD137 Tumor necrosis factor receptor superfamily member 9 (TNFRSF9)...

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Multiple Spanning Tree Protocol

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Fa0/13 Root FWD 200000 128.13 P2p Fa0/16 Altn BLK 200000 128.16 P2p ##### MST1 vlans mapped: 20,40 Bridge address 000e.8316.f500 priority 32769 (32768 sysid...

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TRAIL

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to death. Feb 2016 Song JJ, Lee YJ (May 2008). "Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily"...

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SAV1

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Verhagen AM, Vaux DL (2006). "Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its...

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WWTR1

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of which is made up of the serine-threonine kinases, STK3/MST2 and STK4/MST1, which when active and complexed with the regulatory protein, SAV1, will...

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Histone H2B

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elongation. If cells receive multiple apoptotic stimuli, caspase-3 activates the Mst1 kinase, which phosphorylates the serine at position 14 in all histone H2B...

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List of primary immunodeficiencies

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syndrome MALT1 deficiency BCL10 deficiency BCL11B deficiency CARD11 deficiency MST1 deficiency TCRα deficiency LCK deficiency IL-21 deficiency IL-21R deficiency...

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Kringle domain

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family S1A. ATF; F12; F2; HABP2; HGF; HGFAC; KREMEN1; KREMEN2; LPA; LPAL2; MST1; PIK3IP1; PLAT; PLAU; PLG; PRSS12; ROR1; ROR2; Fujikawa K, McMullen BA (1985)...

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RASSF5

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M, Khoklatchev A, Ortiz-Vega S, Avruch J (Jul 2004). "Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1...

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MAP4K2

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Jung-Soon; Lu, Wenqi (2015-10-05). "MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway". Nature Communications. 6: 8357...

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RASSF9

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M, Kinashi T (September 2006). "Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion"...

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Hartmut Zohm

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location missing publisher (link) H. Zohmthe ASDEX Upgrade Team; the EUROfusion MST1 Team (2015). "Recent ASDEX Upgrade research in support of ITER and DEMO"...

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USF1

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regulatory subunits. In pancreatic cells, CK2 phosphorylates USF1, PDX1 and MST1 to suppress insulin expression. Transforming growth factor β 1 (TGF beta...

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