Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded by the MST1 (macrophage-stimulating 1) gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000173531 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000032591 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Gerber MJ, Drabkin HA, Firnhaber C, Miller YE, Scoggin CH, Smith DI (Oct 1988). "Regional localization of chromosome 3-specific DNA fragments by using a hybrid cell deletion mapping panel". Am J Hum Genet. 43 (4): 442–51. PMC 1715492. PMID 2902784.
^Yoshimura T, Yuhki N, Wang MH, Skeel A, Leonard EJ (Aug 1993). "Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3". J Biol Chem. 268 (21): 15461–8. doi:10.1016/S0021-9258(18)82279-7. PMID 8393443.
protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded by the MST1 (macrophage-stimulating 1) gene. GRCh38: Ensembl release 89: ENSG00000173531...
which Hpo phosphorylates (Drosophila) the protein kinase Warts (Wts). Hpo (MST1/2 in mammals) is a member of the Ste-20 family of protein kinases. This highly...
knockdown of Mst1 expression. Although Rap1 and RAPL have been shown to regulate both LFA-1 affinity and clustering, overexpression of Mst1 only enhances...
phosphorylate Ste20-like kinases, MST1/2, at their activation loops (Thr183 for MST1 and Thr180 for MST2). Active MST1/2 then phosphorylate SAV1 and MOB1A/B...
Figeys D, et al. (December 2002). "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis". The Journal of Biological Chemistry. 277 (50):...
binding to growth-controlling genes. The serine/threonine kinase Hippo (Mst1/Mst2 encoded by the STK4 and STK3 genes respectively in mammals) activates...
MST2, as well as lower kinase activity compared to both MST2/MST2 and MST1/MST1 homodimers. In addition to activation by straurosporine and FAS ligand...
MST3K), an American television comedy series. Macrophage-stimulating 1 (MST1), gene encoding the macrophage-stimulating protein This disambiguation page...
Daniel; Avruch Joseph (Dec 2002). "Death-associated protein 4 binds MST1 and augments MST1-induced apoptosis". J. Biol. Chem. 277 (50). United States: 47991–8001...
to death. Feb 2016 Song JJ, Lee YJ (May 2008). "Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily"...
Verhagen AM, Vaux DL (2006). "Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its...
of which is made up of the serine-threonine kinases, STK3/MST2 and STK4/MST1, which when active and complexed with the regulatory protein, SAV1, will...
elongation. If cells receive multiple apoptotic stimuli, caspase-3 activates the Mst1 kinase, which phosphorylates the serine at position 14 in all histone H2B...
M, Khoklatchev A, Ortiz-Vega S, Avruch J (Jul 2004). "Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1...
Jung-Soon; Lu, Wenqi (2015-10-05). "MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway". Nature Communications. 6: 8357...
M, Kinashi T (September 2006). "Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion"...
location missing publisher (link) H. Zohmthe ASDEX Upgrade Team; the EUROfusion MST1 Team (2015). "Recent ASDEX Upgrade research in support of ITER and DEMO"...