PRKRIR information

THAP12
Identifiers
Aliases	THAP12, DAP4, P52rIPK, THAP0, PRKRIR, THAP domain containing 12
External IDs	OMIM: 607374; MGI: 1920231; HomoloGene: 37952; GeneCards: THAP12; OMA:THAP12 - orthologs
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	98,367,269 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus epididymis; ; trabecular bone; ; caput epididymis; ; retinal pigment epithelium; ; secondary oocyte; ; ganglionic eminence; ; body of pancreas; ; lactiferous duct; ; superficial temporal artery;
	Top expressed in
	triceps brachii muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; vastus lateralis muscle; ; gastrocnemius muscle; ; digastric muscle; ; intercostal muscle; ; ankle; ; tibialis anterior muscle; ; plantaris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; nucleic acid binding; protein dimerization activity; protein binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cytoplasm;
Biological process	negative regulation of cell population proliferation; signal transduction; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	5612
	72981
	n/a
	ENSMUSG00000030753
	O43422
	Q9CUX1
	NM_004705
	NM_028410; NM_001355114
	NP_004696
	NP_082686; NP_001342043
	Wikidata
View/Edit Human	View/Edit Mouse

52 kDa repressor of the inhibitor of the protein kinase is an enzyme that in humans is encoded by the PRKRIR gene.^[4]^[5]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030753 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gale M Jr; Blakely CM; Hopkins DA; Melville MW; Wambach M; Romano PR; Katze MG (Feb 1998). "Regulation of interferon-induced protein kinase PKR: modulation of P58IPK inhibitory function by a novel protein, P52rIPK". Mol Cell Biol. 18 (2): 859–71. doi:10.1128/mcb.18.2.859. PMC 108797. PMID 9447982.
^ "Entrez Gene: PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)".

and 3 Related for: PRKRIR information