USF1 information

USF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AN4
Identifiers
Aliases	USF1, FCHL, FCHL1, HYPLIP1, MLTF, MLTFI, UEF, bHLHb11, upstream transcription factor 1
External IDs	OMIM: 191523 MGI: 99542 HomoloGene: 31426 GeneCards: USF1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	161,045,977 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	171,246,710 bp
RNA expression pattern
	Top expressed in
	monocyte; ; right lung; ; upper lobe of left lung; ; appendix; ; spleen; ; bone marrow cells; ; ganglionic eminence; ; right lobe of liver; ; body of stomach; ; anterior pituitary;
	Top expressed in
	urethra; ; superior frontal gyrus; ; lip; ; yolk sac; ; morula; ; male urethra; ; neural tube; ; lamina propria of urinary bladder; ; thymus; ; ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; protein dimerization activity; DNA-binding transcription factor activity; histone deacetylase binding; bHLH transcription factor binding; protein binding; protein heterodimerization activity; enzyme binding; double-stranded DNA binding; protein kinase binding; protein homodimerization activity; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; sequence-specific DNA binding; identical protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein-containing complex binding;
Cellular component	transcription regulator complex; nucleus; NURF complex; Set1C/COMPASS complex; nucleoplasm;
Biological process	carbon catabolite regulation of transcription; negative regulation of fibrinolysis; response to hypoxia; regulation of transcription, DNA-templated; glucose homeostasis; regulation of transcription by RNA polymerase II; late viral transcription; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription, DNA-templated; regulation of transcription from RNA polymerase II promoter by glucose; glucose metabolic process; cellular response to insulin stimulus; positive regulation of transcription by RNA polymerase II; positive regulation of transcription from RNA polymerase II promoter by glucose; lipid homeostasis; response to UV;
	Sources:Amigo / QuickGO
Orthologs
	7391
	22278
	ENSG00000158773
	ENSMUSG00000026641
	P22415
	Q61069
	NM_207005; NM_001276373; NM_007122
	NM_009480; NM_001305676; NM_001305677; NM_001305678
	NP_001263302; NP_009053; NP_996888
	NP_001292605; NP_001292606; NP_001292607; NP_033506
	Wikidata
View/Edit Human	View/Edit Mouse

Upstream stimulatory factor 1 is a protein that in humans is encoded by the USF1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000158773 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026641 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shieh BH, Sparkes RS, Gaynor RB, Lusis AJ (April 1993). "Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23". Genomics. 16 (1): 266–268. doi:10.1006/geno.1993.1174. PMID 8486371.
^ "Entrez Gene: USF1 upstream transcription factor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000158773 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026641 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8486371-5] Shieh BH, Sparkes RS, Gaynor RB, Lusis AJ (April 1993). "Localization of the gene-encoding upstream stimulatory factor (USF) to human chromosome 1q22-q23". Genomics. 16 (1): 266–268. doi:10.1006/geno.1993.1174. PMID 8486371.

[entrez-6] "Entrez Gene: USF1 upstream transcription factor 1".

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List of human transcription factors

Nuclear receptor

Homeobox

Zinc finger

Fatty acid synthase

CREB

Chromosome 1

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FOXP3

Transcription factor

Insulin regulatory sequence