Ketazolam information

Ketazolam
Clinical data
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of; administration	Oral
ATC code	N05BA10 (WHO) ;
Legal status
Legal status	BR: Class B1 (Psychoactive drugs); CA: Schedule IV; DE: Prescription only (Anlage III for higher doses); US: Schedule IV;
Pharmacokinetic data
Metabolism	Hepatic
Elimination half-life	26–200 hours
Excretion	Renal
Identifiers
	IUPAC name 11-chloro-2,8-dimethyl-12b-phenyl-6H-[1,3]oxazino[3,2-d][1,4]benzodiazepine-4,7-dione;
CAS Number	27223-35-4 ;
PubChem CID	33746;
DrugBank	DB01587 ;
ChemSpider	31110 ;
UNII	92A214MD7Y;
KEGG	D04650 ;
ECHA InfoCard	100.043.937
Chemical and physical data
Formula	C20H17ClN2O3
Molar mass	368.82 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES ClC1=CC2=C(N(C)C(CN3C(C=C(C)OC32C4=CC=CC=C4)=O)=O)C=C1;
	InChI InChI=1S/C20H17ClN2O3/c1-13-10-18(24)23-12-19(25)22(2)17-9-8-15(21)11-16(17)20(23,26-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3 ; Key:PWAJCNITSBZRBL-UHFFFAOYSA-N ;
	(verify)

Ketazolam (marketed under the brand names Anseren, Ansieten, Ansietil, Marcen, Sedatival, Sedotime, Solatran and Unakalm) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.

^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^ Vega D, Fernández D, Echeverría G (July 2001). "Ketazolam". Acta Crystallographica Section C. 57 (Pt 7): 848–850. doi:10.1107/S0108270101006175. PMID 11443263.

[1] Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.

[2] Vega D, Fernández D, Echeverría G (July 2001). "Ketazolam". Acta Crystallographica Section C. 57 (Pt 7): 848–850. doi:10.1107/S0108270101006175. PMID 11443263.

Ketazolam information

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Clinical data


AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Oral
ATC code	N05BA10 (WHO)
Legal status
Legal status	BR: Class B1 (Psychoactive drugs)^[1] CA: Schedule IV DE: Prescription only (Anlage III for higher doses) US: Schedule IV
Pharmacokinetic data
Metabolism	Hepatic
Elimination half-life	26–200 hours
Excretion	Renal
Identifiers
IUPAC name 11-chloro-2,8-dimethyl-12b-phenyl-6H-[1,3]oxazino[3,2-d][1,4]benzodiazepine-4,7-dione^[2]
CAS Number	27223-35-4^Y
PubChem CID	33746
DrugBank	DB01587^Y
ChemSpider	31110^Y
UNII	92A214MD7Y
KEGG	D04650^Y
ECHA InfoCard	100.043.937
Chemical and physical data
Formula	C₂₀H₁₇ClN₂O₃
Molar mass	368.82 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES ClC1=CC2=C(N(C)C(CN3C(C=C(C)OC32C4=CC=CC=C4)=O)=O)C=C1
InChI InChI=1S/C20H17ClN2O3/c1-13-10-18(24)23-12-19(25)22(2)17-9-8-15(21)11-16(17)20(23,26-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3^Y Key:PWAJCNITSBZRBL-UHFFFAOYSA-N^Y
(verify)