Induced cell cycle arrest information

Induced cell cycle arrest is the use of a chemical or genetic manipulation to artificially halt progression through the cell cycle. Cellular processes...

segregation, and inducing a cell cycle arrest in response until the defects are repaired. The main mechanism of action of the cell cycle checkpoints is...

cancer cells without affecting healthy tissues. In vitro testing demonstrated that AOH1996 inhibited the growth and induced cell cycle arrest and apoptotic...

al. also found that γ-irradiation of fibroblasts induced a p53 and p21 dependent cell cycle arrest, here p21 was found bound to inactive cyclin E/CDK2...

dividing or non-dividing cells such as T cells or macrophages. Vpr also induces G2 cell cycle arrest and apoptosis in proliferating cells, which can result in...

the cell cycle also regulate pluripotency. Thus, manipulation of relevant genes can maintain pluripotency and reprogram somatic cells to an induced pluripotent...

and cell cycle checkpoint response. Activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death...

strand breaks can lead to cell cycle arrest in somatic cells and cause cell death. Due to its ability to induce cell cycle arrest, ionizing radiation is...

Neuronal cell cycle represents the life cycle of the biological cell, its creation, reproduction and eventual death. The process by which cells divide into...

S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication...

Cell synchronization is a process by which cells in a culture at different stages of the cell cycle are brought to the same phase. Cell synchrony is a...

The cell cycle, or cell-division cycle, is the series of events that take place in a cell that causes it to divide into two daughter cells. These events...

complexes displaces p53 and activates the p53 pathway, leading to cell cycle arrest and apoptosis. Many different methods can be used either to stimulate...

cell cycle regulation of K562 cells. This gene targets the cyclin-dependent kinase inhibitor, p21, and causes cell differentiation, cell cycle arrest...

pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. When the cell is ready to divide, pRb is...

phase describes a cellular state outside of the replicative cell cycle. Classically[when?], cells were thought to enter G0 primarily due to environmental...

Cell division is the process by which a parent cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which...

quercetin contained in T. sinensis leaves can induce cell cycle arrest and lead to apoptosis of cells. In Chinese literature, Toona sinensis is often...

(September 1994). "p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest". Nature. 371 (6494): 257–61. Bibcode:1994Natur.371..257H. doi:10...

totipotent blastomeres from 2-cell stage embryos can arise spontaneously in mouse embryonic stem cell cultures and also can be induced to arise more frequently...

first of four phases of the cell cycle that takes place in eukaryotic cell division. In this part of interphase, the cell synthesizes mRNA and proteins...

present). Mouse ES cells lack a G1 checkpoint and do not undergo cell cycle arrest upon acquiring DNA damage. Rather they undergo programmed cell death (apoptosis)...

germ cell cycle are the egg or sperm. Under special conditions in vitro germ cells can acquire properties similar to those of embryonic stem cells (ESCs)...

Cronin M, Mendelsohn J (April 1986). "EGF induces cell cycle arrest of A431 human epidermoid carcinoma cells". Journal of Cellular Physiology. 127 (1):...

the cell cycle checkpoint transition checkpoint from the G1 to the S phase of the cell cycle. These cell cycle inhibitors work by inducing cell cycle arrest...

these two kinases causes the eventual arrest of the cell cycle. Depending on the severity of the DNA damage, the cells may no longer be able to undergo repair...

suppressor by inhibiting ribosome biogenesis or initiating p53-dependent cell cycle arrest and apoptosis, respectively. p14ARF is an atypical protein, in terms...