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G1 phase information


Mitosis in an animal cell (phases ordered counter-clockwise), with G1 labeled at left.

The G1 phase, gap 1 phase, or growth 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division. In this part of interphase, the cell synthesizes mRNA and proteins in preparation for subsequent steps leading to mitosis. G1 phase ends when the cell moves into the S phase of interphase. Around 30 to 40 percent of cell cycle time is spent in the G1 phase.

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G1 phase

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The G1 phase, gap 1 phase, or growth 1 phase, is the first of four phases of the cell cycle that takes place in eukaryotic cell division. In this part...

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G0 phase

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extended G1 phase or in a cell cycle phase distinct from G1 – termed G0. Subsequent research pointed to a restriction point (R-point) in G1 where cells...

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Cell cycle

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distinct phases: G1 phase, S phase (synthesis), G2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself...

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S phase

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S phase (Synthesis phase) is the phase of the cell cycle in which DNA is replicated, occurring between G1 phase and G2 phase. Since accurate duplication...

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Induced cell cycle arrest

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methionine, some cells arrest in early G1 phase. S phase follows G1 phase via the G1/S transition and precedes G2 phase in interphase and is the part of the...

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Cell biology

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cell cycle is divided into four distinct phases: G1, S, G2, and M. The G phase – which is the cell growth phase – makes up approximately 95% of the cycle...

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Cell cycle checkpoint

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cycle consists of four main stages: G1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes...

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Cell division

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meiosis, and cytokinesis. Interphase consists of three main phases: G1, S, and G2. G1 is a time of growth for the cell where specialized cellular functions...

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G1

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G1, G01, G.I, G-1, or G One may refer to: G1 phase, in the cellular cycle G1 regulatory sequence for the insulin gene ATC code G01 Gynecological antiinfectives...

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G2 phase

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end of S phase after DNA replication, in response to phosphorylation of transcription factors such as NF-Y, FoxM1 and B-Myb by upstream G1 and G1/S cyclin-CDK...

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DNA end resection

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throughout the cell cycle, but it is critical to DNA repair during the G1 phase. In G1 phase there is no sister chromatids to repair DSBs via the HR pathway...

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Mitosis

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organelles. However, chromosomes are replicated only during the S phase. Thus, a cell grows (G1), continues to grow as it duplicates its chromosomes (S), grows...

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Interphase

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Interphase is the active portion of the cell cycle that includes the G1, S, and G2 phases, where the cell grows, replicates its DNA, and prepares for mitosis...

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Restriction point

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restriction point (R), also known as the Start or G1/S checkpoint, is a cell cycle checkpoint in the G1 phase of the animal cell cycle at which the cell becomes...

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Stem cell

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transitions between phases: Cyclin D and Cdk4/6 are active in the G1 phase, while Cyclin E and Cdk2 are active during the late G1 phase and S phase; and Cyclin...

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DNA replication

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complex formation. If environmental conditions are right in late G1 phase, the G1 and G1/S cyclin-Cdk complexes are activated, which stimulate expression...

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Cyclin E

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of the cyclin family. Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle that determines initiation...

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P16

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division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby acting as a tumor suppressor. It is encoded by the CDKN2A...

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Cyclin D1

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is a protein required for progression through the G1 phase of the cell cycle. During the G1 phase, it is synthesized rapidly and accumulates in the nucleus...

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Embryonic stem cell

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GSK-3 inhibitor CHIR99021. ESCs divide very frequently due to a shortened G1 phase in their cell cycle. Rapid cell division allows the cells to quickly grow...

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Centrosome cycle

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maturation in the G2 phase, centrosome separation in the mitotic phase, and centrosome disorientation in the late mitotic phaseG1 phase. Centrioles are generated...

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Minichromosome maintenance

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each stage is a central feature of eukaryotic DNA replication. During G1 phase, the two head-to-head Mcm2-7 rings serve as the scaffold for the assembly...

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