Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo.[1][2] Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre-implantation stage have the same moral considerations as embryos in the post-implantation stage of development.[3][4]
Researchers are currently focusing heavily on the therapeutic potential of embryonic stem cells, with clinical use being the goal for many laboratories.[2] Potential uses include the treatment of diabetes and heart disease.[2] The cells are being studied to be used as clinical therapies, models of genetic disorders, and cellular/DNA repair. However, adverse effects in the research and clinical processes such as tumors and unwanted immune responses have also been reported.[5]
^ abc"Stem Cell Basics | STEM Cell Information". stemcells.nih.gov. Archived from the original on 9 June 2022. Retrieved 5 June 2022.
^Baldwing A (2009). "Morality and human embryo research. Introduction to the Talking Point on morality and human embryo research". EMBO Reports. 10 (4): 299–300. doi:10.1038/embor.2009.37. PMC 2672902. PMID 19337297.
^Nakaya, Andrea C. (August 1, 2011). Biomedical ethics. San Diego, CA: ReferencePoint Press. pp. 96. ISBN 978-1601521576.
^Carla A Herberts; Marcel SG Kwa; Harm PH Hermsen (2011). "Risk factors in the development of stem cell therapy". Journal of Translational Medicine. 9 (29): 29. doi:10.1186/1479-5876-9-29. PMC 3070641. PMID 21418664.
and 21 Related for: Embryonic stem cell information
produce more of the same stemcell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they...
resembling totipotent blastomeres from 2-cell stage embryos can arise spontaneously in mouse embryonicstemcell cultures and also can be induced to arise...
well-known type of pluripotent stemcell is the embryonicstemcell. However, since the generation of embryonicstemcells involves destruction (or at least...
controversy focuses on embryonicstemcells. Not all stemcell research involves human embryos. For example, adult stemcells, amniotic stemcells, and induced...
organism is known as pluripotent. Such cells are called meristematic cells in higher plants and embryonicstemcells in animals, though some groups report...
glia of the nervous system of all animals during embryonic development. Some neural progenitor stemcells persist in highly restricted regions in the adult...
somatic stemcells (from Greek σωματικóς, meaning of the body), they can be found in juvenile, adult animals, and humans, unlike embryonicstemcells. Scientific...
concerning embryonicstemcells (ESCs) and the destruction of viable embryos for medical use, though questions remain on how homologous the two cell types...
germ cell cycle are the egg or sperm. Under special conditions in vitro germ cells can acquire properties similar to those of embryonicstemcells (ESCs)...
from that stemcell. Embryonicstemcells are pluripotent stemcells derived from the inner cell mass of the blastocyst. These stemcells can differentiate...
development of stemcell biology. Fibroblast Embryonicstemcell Jian-ming Xu (2005). "Preparation, Culture, and Immortalization of Mouse Embryonic Fibroblasts"...
Hematopoietic stemcells (HSCs) are the stemcells that give rise to other blood cells. This process is called haematopoiesis. In vertebrates, the first...
embryonicstemcells are taken from embryoblasts, induced pluripotent stemcells are undifferentiated from somatic adult cells. Stemcells are cells found...
Christian Coalition voter guide indicating that she would vote to ban embryonicstem-cell research. In 2015, she co-sponsored legislation to amend the 14th...
approved the first clinical trial in the United States involving human embryonicstemcells on January 23, 2009. Geron Corporation, a biotechnology firm located...
subsequently raised in these TE cells, indicating Cdx2 plays a role in suppressing Oct4 in this cell lineage. Moreover, embryonicstemcells can be generated from...
Induced stemcells (iSC) are stemcells derived from somatic, reproductive, pluripotent or other cell types by deliberate epigenetic reprogramming. They...
Stemcell markers are genes and their protein products used by scientists to isolate and identify stemcells. Stemcells can also be identified by functional...
sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting...
senate, he subsequently voted against expanding federal funds for embryonicstemcell research in July 2006. Actor Michael J. Fox, who has Parkinson's...