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Glycosphingolipid information


Sphingosine

Glycosphingolipids are a subtype of glycolipids containing the amino alcohol sphingosine. They may be considered as sphingolipids with an attached carbohydrate. Glycosphingolipids are a group of lipids (more specifically, sphingolipids) and are a part of the cell membrane. They consist of a hydrophobic ceramide part and a glycosidically bound carbohydrate part. This oligosaccharide content remains on the outside of the cell membrane where it is important for biological processes such as cell adhesion or cell–cell interactions. Glycosphingolipids play also important role in oncogenesis and ontogenesis.

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Glycosphingolipid

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Glycosphingolipids are a subtype of glycolipids containing the amino alcohol sphingosine. They may be considered as sphingolipids with an attached carbohydrate...

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Cerebroside

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Cerebrosides (monoglycosylceramides) are a group of glycosphingolipids which are important components of animal muscle and nerve cell membranes. They consist...

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P1PK blood group system

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blood group system consists of three glycosphingolipid antigens: Pk, P1 and NOR. In addition to glycosphingolipids, terminal Galα1→4Galβ structures are...

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Glycosphingolipid deacylase

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a glycosphingolipid deacylase (EC 3.5.1.69) is an enzyme that catalyzes a chemical reaction that cleaves gangliosides and neutral glycosphingolipids, releasing...

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Ceramidase

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Ceramidase (EC 3.5.1.23, acylsphingosine deacylase, glycosphingolipid ceramide deacylase) is an enzyme which cleaves fatty acids from ceramide, producing...

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Sphingolipid

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respectively. Cerebrosides and globosides are collectively known as glycosphingolipids. The long-chain bases, sometimes simply known as sphingoid bases,...

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Globoside

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Globosides are a sub-class of the lipid class glycosphingolipid with three to nine sugar molecules as the side chain (or R group) of ceramide. The sugars...

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Glycolipid

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with the sulfur cycle in plants. Glycosphingolipids: a sub-group of glycolipids based on sphingolipids. Glycosphingolipids are mostly located in nervous...

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Lipid

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fatty acyl CoA, then converted into ceramides, phosphosphingolipids, glycosphingolipids and other compounds. The major sphingoid base of mammals is commonly...

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Fifth disease

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the host cell. After gaining access to the host cell, B19V binds to glycosphingolipid globoside (blood group P antigen) targeting erythroid lineage in the...

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Epidermis

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non-polar lipids and arranged parallel to the cell surface. For example glycosphingolipids become ceramides and phospholipids become free fatty acids. spinous...

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Pleurotus eryngii

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Kiyoshi; Suzuki, Akemi; Kushi, Yasunori (August 2008). "Mushroom acidic glycosphingolipid induction of cytokine secretion from murine T cells and proliferation...

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Mitochondrion

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phospholipid biosynthetic pathways, ceramide and cholesterol metabolism, and glycosphingolipid anabolism. Such trafficking capacity depends on the MAM, which has...

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Ganglioside

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A ganglioside is a molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids (e.g. N-acetylneuraminic acid...

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Shiga toxin

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toxicon.2009.11.021. PMID 2047652. Gastric adenocarcinomas express the glycosphingolipid Gb3/CD77: Targeting of gastric cancer cells with Shiga toxin B-subunit...

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Cayman Chemical Company

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biochemical company offering a comprehensive line of sphingolipids, glycosphingolipids, gangliosides, globotriaosylceramides, fatty acids, and sterols. Freed...

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UGCG

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glucosyltransferase is an enzyme that in humans is encoded by the UGCG gene. Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar...

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Eastern blot

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Schoenenberger, C; Ball, R; Braun, DG; Rosenfelder, G; et al. (1984). "Glycosphingolipid-blotting: an immunological detection procedure after separation by...

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ABO blood group system

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literature claiming that the ABH substances were all attached to glycosphingolipids, Finne et al. (1978) found that the human erythrocyte glycoproteins...

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Lipid signaling

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most widely distributed glycosphingolipids in cells serving as precursors for the formation of over 200 known glycosphingolipids. GluCer is formed by the...

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Interleukin 2

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Molecular function cytokine activity interleukin-2 receptor binding glycosphingolipid binding kinase activator activity growth factor activity kappa-type...

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GM3

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condensed to NANA-Gal-Glc-ceramide. GM3 is the most common membrane-bound glycosphingolipid in tissues, composed of three monosaccharide groups attached to a...

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