Gene targeting information

The two most established forms of gene editing are gene-targeting and targeted-mutagenesis. While gene targeting relies on the Homology Directed Repair...

well as reduced off target effects. This could be used for research purposes, by targeting mutations to specific genes, and in gene therapy. By inserting...

Targeting may refer to: Gene targeting Protein targeting Behavioral targeting Targeted advertising Target market Geotargeting, in internet marketing Targeting...

word gene (Greek: γένος, génos; generation, or birth, or gender) has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is...

Gene knockouts (also known as gene deletion or gene inactivation) are a widely used genetic engineering technique that involves the targeted removal or...

Homologous recombination is also used in gene targeting, a technique for introducing genetic changes into target organisms. For their development of this...

while having an increased ability to avoid degradation by target cell lysosomes. Gene targeting Minicircle Plasmid Transgene Vector (molecular biology)...

exist for integration. To create a stable mutant line, gene targeting can be used to insert a gene of interest into a particular location of the C. merolae...

targeted to a specific location. The technique of gene targeting uses homologous recombination to make desired changes to a specific endogenous gene....

moss's specific genes are deleted or inactivated ("knocked out"), for example by gene targeting or other methods. After the deletion of a gene, the knockout...

modulate gene expression by targeting dCas9-repressors or activators toward promoter or transcriptional start sites of target genes. For repressing genes Cas9...

the virus family Caliciviridae, by targeting both its structural and non-structural genes. By targeting the NTPase gene, one dose of siRNA 4 hours pre-infection...

the role of individual genes in living organisms. It differs from traditional gene knockout because it targets specific genes at specific times rather...

of early and late genes. Silencing of IE gene expression through antisense oligonucleotides, RNA interference, and gene-targeting ribosomes have been...

specimens. Early techniques randomly inserted the genes into the genome. Advances allow targeting specific locations, which reduces unintended side effects...

mouse and the related technology of gene targeting, a method of using embryonic stem cells to create specific gene modifications in mice. In 2007, the...

altering animal genomes than previously used, and the technique behind gene targeting and knockout mice. He received the Nobel Prize in Physiology or Medicine...

cell-specific targeting and subcellular trafficking control. Methods for non-viral gene therapy include the injection of naked DNA, electroporation, the gene gun...

Talk: "The Birth of Gene Targeting" Mario R. Capecchi on Nobelprize.org including the Nobel Lecture on 7 December 2007 Gene Targeting 1977 - Present Eccles...

Creating Knockout Mice for Targeting Vector from Knockout Mice Research(KMR) – A website for ordering embryonic stem cells, targeting vectors and transgenic...

the development and application of molecularly targeted therapies. Molecular oncology has identified genes that are involved in the development of cancer...

c-myc gene by one of three chromosomal translocations which place the myc gene under the control of an immunoglobulin gene enhancer. The MYC gene is found...

the loop to target genes outside the loop. Loops with CTCF and cohesin at the start and end of the loop that restrict enhancer-gene targeting are "insulated...

that an exogenous DNA sequence can be targeted to a specific genomic position (a technique called gene targeting) to create knockout mosses. This approach...

RNA-induced gene activation" or RNAa. It has been shown that dsRNAs targeting gene promoters induce potent transcriptional activation of associated genes. RNAa...