Kyoto Prize (1996) Franklin Medal (1997) Albert Lasker Award for Basic Medical Research (2001) Massry Prize (2002) Wolf Prize in Medicine (2002) Nobel Prize in Physiology or Medicine (2007)
Scientific career
Fields
Genetics
Institutions
Harvard Medical School University of Utah
Thesis
On the Mechanism of Suppression and Polypeptide Chain Initiation(1967)
Doctoral advisor
James D. Watson
Website
capecchi.genetics.utah.edu
Mario Ramberg Capecchi (born 6 October 1937) is an Italian-born molecular geneticist and a co-awardee of the 2007 Nobel Prize in Physiology or Medicine for discovering a method to create mice in which a specific gene is turned off, known as knockout mice.[1][2][3][4][5][6] He shared the prize with Martin Evans and Oliver Smithies.[7] He is currently Distinguished Professor of Human Genetics and Biology at the University of Utah School of Medicine.[8][9][10][11][12]
^Thomas, K. R.; Capecchi, M. R. (1987). "Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells". Cell. 51 (3): 503–512. doi:10.1016/0092-8674(87)90646-5. PMID 2822260. S2CID 31961262.
^Mansour, S. L.; Thomas, K. R.; Capecchi, M. R. (1988). "Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes". Nature. 336 (6197): 348–352. Bibcode:1988Natur.336..348M. doi:10.1038/336348a0. PMID 3194019. S2CID 2997260.
^Capecchi, M. R. (1980). "High efficiency transformation by direct microinjection of DNA into cultured mammalian cells". Cell. 22 (2 Pt 2): 479–488. doi:10.1016/0092-8674(80)90358-x. PMID 6256082. S2CID 2189404.
^Chisaka, O.; Capecchi, M. R. (1991). "Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5". Nature. 350 (6318): 473–479. Bibcode:1991Natur.350..473C. doi:10.1038/350473a0. PMID 1673020. S2CID 972118.
^Thomas, K. R.; Folger, K. R.; Capecchi, M. R. (1986). "High frequency targeting of genes to specific sites in the mammalian genome". Cell. 44 (3): 419–428. doi:10.1016/0092-8674(86)90463-0. PMID 3002636. S2CID 30570106.
^"The Nobel Prize in Physiology or Medicine 2007". Nobelprize.org. Retrieved 2007-10-08.
^Mario Capecchi publications indexed by Microsoft Academic
^Kain, K. (2008). "The first transgenic mice: An interview with Mario Capecchi". Disease Models and Mechanisms. 1 (4–5): 197–201. doi:10.1242/dmm.001966. PMC 2590805. PMID 19093023.
^Cohen-Tannoudji, M. (2007). "Prix Nobel de Médecine 2007". Médecine/Sciences. 23 (12): 1159–1161. doi:10.1051/medsci/200723121159. PMID 18154719.
Mario Ramberg Capecchi (born 6 October 1937) is an Italian-born molecular geneticist and a co-awardee of the 2007 Nobel Prize in Physiology or Medicine...
Capecchi (born 1974), Italian footballer MarioCapecchi (born 1937), Italian-born American geneticist Renato Capecchi (1923–1998), Italian opera singer, actor...
heads to the north on MarioCapecchi Drive. This road was previously known as Wasatch Drive, but was renamed after MarioCapecchi, a researcher at the...
this technique, MarioCapecchi, Martin Evans and Oliver Smithies were awarded the 2007 Nobel Prize for Physiology or Medicine; Capecchi and Smithies independently...
electrophoresis in 1955, and for the discovery, simultaneously with MarioCapecchi and Martin Evans, of the technique of homologous recombination of transgenic...
interviewed several high-profile scientists including Anne McLaren, MarioCapecchi and Oliver Smithies. In 2002 she was appointed chief editor of Nature...
Change Physics – Albert Fert, Peter Grünberg Physiology or Medicine – MarioCapecchi, Oliver Smithies, and Sir Martin Evans additive manufacturing colony...
cultivate them in a laboratory in 1981. He is also known, along with MarioCapecchi and Oliver Smithies, for his work in the development of the knockout...
introduce genetic modifications in mice through embryonic stem cells, MarioCapecchi, Martin Evans and Oliver Smithies were awarded the 2007 Nobel Prize...
differential geometry, partial differential equations and their applications MarioCapecchi (born 1941) - Nobel Prize 2007 winner for medicine Nicholas R. Cozzarelli...
1979) Vice Chair of the Board of Governors of the Federal Reserve. MarioCapecchi, (class of 1956) winner of the 2007 Nobel Prize in Medicine Kathleen...
students subsequently became notable in their own right including, MarioCapecchi, Bob Horvitz, Peter B. Moore and Joan Steitz. Besides numerous PhD students...
in detecting gravitational waves". The Salt Lake Tribune. "Dr. MarioCapecchi". capecchi.genetics.utah.edu. Archived from the original on November 22,...
college is affiliated with two Nobel Prize winners, José Ramos-Horta and MarioCapecchi. Antioch College is on the site of a short-lived Owenite community,...
13 Nobel Prize winners; John Gurdon, Shinya Yamanaka, Bruce Beutler, MarioCapecchi, Andrew Fire, Richard Axel, Eric Wieschaus, Phillip Sharp, Robert Lefkowitz...
Information Center. The Nobel Prize laureates include James D. Watson, MarioCapecchi, Oliver Smithies, Paul Berg, E. Donnall Thomas, and Walter Gilbert....
endogenous genes. The second approach, pioneered by Oliver Smithies and MarioCapecchi, involves modifying embryonic stem cells with a DNA construct containing...
development of electron microscopy and color television. He was the uncle of MarioCapecchi, a 2007 Nobel laureate. Ramberg was born in Florence, Italy to American...
psychiatrist and psychoanalyst Joseph Young Bergen (1872), botanist MarioCapecchi (B.S. 1961), PhD Harvard University, co-recipient of the Nobel Prize...
known as "Veronese", painter Lou Campi (1905–1989), professional bowler MarioCapecchi (born 1937), Nobel prize in Medicine, 2007 Giovanni Francesco Caroto...
Barry Marshall / Robin Warren 2006: Andrew Fire / Craig Mello 2007: MarioCapecchi / Martin Evans / Oliver Smithies 2008: Harald zur Hausen / Luc Montagnier...
for medical students, residents, and fellows at the school. In 2007, MarioCapecchi, distinguished professor of human genetics and biology, was awarded...
prize in this category, for the discovery of genetic transposition. MarioCapecchi, Martin Evans, and Oliver Smithies were awarded the prize in 2007 for...
Grameen Bank Edmund Phelps 2007 Albert Fert; Peter Grünberg Gerhard Ertl MarioCapecchi; Martin Evans; Oliver Smithies Doris Lessing Intergovernmental Panel...
Italian Americans became Nobel Prize laureates in the post-war decades: MarioCapecchi, Renato Dulbecco, Riccardo Giacconi, Salvatore Luria, Franco Modigliani...
recognized in 2007 with the Nobel Prize in Physiology or Medicine to Drs. MarioCapecchi, Martin Evans, and Oliver Smithies. In developing small molecule drugs...
cardiovascular diseases, and neurological disorders.[citation needed] MarioCapecchi, Sir Martin J. Evans, and Oliver Smithies performed groundbreaking research...
2003 Robert G. Roeder 2002 James E. Rothman Randy W. Schekman 2001 MarioCapecchi Martin Evans Oliver Smithies 2000 Aaron Ciechanover Avram Hershko Alexander...
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