Factor X deficiency is inherited in an autosomal recessive manner
Specialty
Hematology, medical genetics
Factor X deficiency (X as Roman numeral ten) is a bleeding disorder characterized by a lack in the production of factor X (FX), an enzyme protein that causes blood to clot in the coagulation cascade. Produced in the liver FX when activated cleaves prothrombin to generate thrombin in the intrinsic pathway of coagulation. This process is vitamin K dependent and enhanced by activated factor V.
The condition may be inherited or, more commonly, acquired.
and 26 Related for: Factor X deficiency information
from congenital deficiency, low factorX levels may occur occasionally in a number of disease states. For example, factorXdeficiency may be seen in amyloidosis...
coagulation factor disorders are the hemophilias. The three main forms are hemophilia A (factor VIII deficiency), hemophilia B (factor IX deficiency or "Christmas...
mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A). Haemophilia...
autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factordeficiency, malabsorption of vitamin B12, and subsequent...
hemophilia A) is a blood clotting disorder caused by a genetic deficiency in clotting factor VIII, thereby resulting in significant susceptibility to bleeding...
The PT evaluates coagulation factors I, II, V, VII and X, while the PTT evaluates coagulation factors I, II, V, VIII, IX, X, XI and XII. The analysis of...
contrast to most other coagulation factors, it is not enzymatically active but functions as a cofactor. Factor V deficiency leads to predisposition for hemorrhage...
refers to a type of vitamin B12 deficiency anemia that results from lack of intrinsic factor. Lack of intrinsic factor is most commonly due to an autoimmune...
medical science, antithrombin deficiency, was identified in 1965, while the most common abnormalities (including factor V Leiden) were described in the...
antecedent (PTA) deficiency or Rosenthal syndrome) is a mild form of haemophilia affecting both sexes, due to factor XI deficiency. It predominantly...
Factor XII deficiency is a deficiency in the production of factor XII (FXII), a plasma glycoprotein and clotting factor that participates in the coagulation...
sheep carrying the gene for factor IX, was produced by Dr Ian Wilmut at the Roslin Institute in 1997. Deficiency of factor IX causes Christmas disease...
Other causes of reactive thrombocythemia include: post surgery, iron deficiency, drugs, and rebound effect after bone marrow suppression. Research suggests...
rises first, since the activated Factor VII is the first to "disappear." In later stages of deficiency, the other factors (which have longer half lives)...
clotting factors or coagulation factors. Genetic disorders, such as hemophilia and Von Willebrand disease, can cause a reduction in clotting factors. Anticoagulants...
factors IX and X. The gene for factor VII is located on chromosome 13 (13q34). Factor VII deficiency (congenital proconvertin deficiency) is rare and inherited...
distinguish factordeficiencies from factor inhibitors, such as lupus anticoagulant, or specific factor inhibitors, such as antibodies directed against factor VIII...
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as a causative factor in schizophrenia is normally suppressed by vitamin D. Those most likely to be affected by vitamin D deficiency are people with...
Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin...
homologous to the corresponding bond cleaved during factor XI activation. Hereditary deficiencies in PK are very rare. They can cause a prolonged APTT...
(5q33-qter). Factor XII deficiency is a rare disorder that is inherited in an autosomal recessive manner. Unlike other clotting factordeficiencies, factor XII...
this exposes the factor IX binding site of the third apple domain, allowing factor XI's protease activity on it. Deficiency of factor XI causes the rare...