3D rendering of four inactivated and three activated platelets
Specialty
Hematology
Histopathological image representing a bone marrow aspirate in a patient with essential thrombocythemia
In hematology, thrombocythemia is a condition of high platelet (thrombocyte) count in the blood. Normal count is in the range of 150×109 to 450×109 platelets per liter of blood,[1] but investigation is typically only considered if the upper limit exceeds 750×109/L.
When the cause is unknown, the term thrombocythemia is used, as either primary thrombocythemia or essential thrombocythemia. The condition arises from a fault in the bone marrow cells leading to over-production of platelets but the cause of the fault is unknown, and this type is not common.[2]
When the cause is known such as another disorder or disease, the term thrombocytosis is preferred, as either secondary or reactive thrombocytosis. Reactive thrombocytosis is the most common type and though it can often have no symptoms it can sometimes predispose to thrombosis. In contrast, thrombocytopenia refers to abnormally low blood platelet numbers in the blood.[2]
^Kumar PJ, Clark ML (2005). "8". Clinical Medicine (Sixth ed.). Elsevier Saunders. pp. 469. ISBN 0-7020-2763-4.
^ ab"Thrombocythemia and Thrombocytosis | National Heart, Lung, and Blood Institute (NHLBI)". www.nhlbi.nih.gov. Archived from the original on 14 June 2019. Retrieved 20 December 2019.
In hematology, thrombocythemia is a condition of high platelet (thrombocyte) count in the blood. Normal count is in the range of 150×109 to 450×109 platelets...
In hematology, essential thrombocythemia (ET) is a rare chronic blood cancer (myeloproliferative neoplasm) characterised by the overproduction of platelets...
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the treatment of essential thrombocytosis (also known as essential thrombocythemia), or overproduction of blood platelets. It also has been used in the...
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all patients progress. Symptoms and presentation can mimic essential thrombocythemia, with the main differentiator for pre-PMF being the presence of fibrosis...
abnormal megakaryocyte function or abnormal platelet function. Essential thrombocythemia (ET) is a disorder characterized by elevated numbers of circulating...
synonymous with idiopathic (as in essential hypertension, essential thrombocythemia, and essential tremor) and the same is true of primary (as in primary...
hemopericardium was noted as an initial manifestation of essential thrombocythemia. Hemopericardium can be diagnosed using echocardiography, a cardiac...
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underlying neoplasms such as polycythemia vera (PV), myelofibrosis, thrombocythemia, or, in rare cases, solid tumors. Alternative root causes other than...
associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is...
polycythemia vera (and the related myeloproliferative disease essential thrombocythemia) is erythromelalgia. This is a burning pain in the hands or feet, usually...
M (September 2003). "Treatment of polycythemia vera and essential thrombocythemia: the role of pipobroman". Leukemia & Lymphoma. 44 (9): 1483–8. doi:10...
fiber peripheral neuropathy of any cause, polycythemia vera, essential thrombocythemia, hypercholesterolemia, mushroom or mercury poisoning, and some autoimmune...
transferase (5%), positive direct Coombs test (4%), increased platelets (thrombocythemia) (2%), increased ALT (7%), increased AST (6%), or increased alkaline...
being studied in psoriasis, polycythemia vera, alopecia, essential thrombocythemia, ulcerative colitis, myeloid metaplasia with myelofibrosis and vitiligo...
the treatment of myeloproliferative neoplasms including essential thrombocythemia, polycythemia vera, myelofibrosis and small-cell lung cancer. Bomedmestat...
Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)". ClinicalTrials.gov. Archived from the...
extreme elevations in platelet count such as those with essential thrombocythemia or polycythemia vera. In 2010, the American Society for Apheresis published...
count may reach exceptionally high levels in people with essential thrombocythemia, a rare blood disease. The platelet count can be reported in units...
high- or intermediate-risk primary or post–polycythemia vera/essential thrombocythemia myelofibrosis have been published in 2011. In the United States, fedratinib...
patients with myeloproliferative neoplasms, polycythemia vera, essential thrombocythemia, or myelofibrosis, who had failed ruxolitinib. "Gandotinib - Eli Lilly"...
Myeloproliferative neoplasms including polycythemia vera and essential thrombocythemia Nonsyndromic hearing loss and deafness, DFNB1 (connexin 26) Parkinson's...
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