Factor XI, or plasma thromboplastin antecedent, is the zymogen form of factor XIa, one of the enzymes involved in coagulation. Like many other coagulation factors, it is a serine protease. In humans, factor XI is encoded by F11 gene.[5][6][7][8]
^ abcGRCh38: Ensembl release 89: ENSG00000088926 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000031645 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Fujikawa K, Chung DW, Hendrickson LE, Davie EW (May 1986). "Amino acid sequence of human factor XI, a blood coagulation factor with four tandem repeats that are highly homologous with plasma prekallikrein". Biochemistry. 25 (9): 2417–24. doi:10.1021/bi00357a018. PMID 3636155.
^Asakai R, Davie EW, Chung DW (Nov 1987). "Organization of the gene for human factor XI". Biochemistry. 26 (23): 7221–8. doi:10.1021/bi00397a004. PMID 2827746.
^Kato A, Asakai R, Davie EW, Aoki N (1989). "Factor XI gene (F11) is located on the distal end of the long arm of human chromosome 4". Cytogenetics and Cell Genetics. 52 (1–2): 77–8. doi:10.1159/000132844. PMID 2612218.
^Buetow KH, Shiang R, Yang P, Nakamura Y, Lathrop GM, White R, Wasmuth JJ, Wood S, Berdahl LD, Leysens NJ (May 1991). "A detailed multipoint map of human chromosome 4 provides evidence for linkage heterogeneity and position-specific recombination rates". American Journal of Human Genetics. 48 (5): 911–25. PMC 1683054. PMID 1673289.
FactorXI, or plasma thromboplastin antecedent, is the zymogen form of factor XIa, one of the enzymes involved in coagulation. Like many other coagulation...
syndrome) is a mild form of haemophilia affecting both sexes, due to factorXI deficiency. It predominantly occurs in Ashkenazi Jews. It is the fourth...
tendency. In 1957, an American group identified the same factor in a Mr. Rufus Stuart. FactorsXI and XIII were identified in 1953 and 1961, respectively...
Activated blood coagulation factorXI may refer to: Coagulation factor IXa, an enzyme Coagulation factor XIa, an enzyme This disambiguation page lists...
protein for factor Xa is increased 1000-fold by the presence of protein Z, while it does not require protein Z for inactivation of factorXI. Defects in...
following coagulation factors: I (fibrinogen), II (prothrombin), V (proaccelerin), VIII (anti-hemophilic factor), X (Stuart–Prower factor), XI (plasma thromboplastin...
antibodies forming against a clotting factor. Other types include haemophilia C, which occurs due to low levels of factorXI, Von Willebrand disease, which occurs...
the coagulation cascade and activates factorXI and prekallikrein in vitro. Factor XII itself is activated to factor XIIa by negatively charged surfaces...
clotting factor that participates in the coagulation cascade and activates factorXI. FXII appears to be not essential for blood clotting, as individuals with...
cleaved to produce kallikrein by activated Factor XII (Hageman factor). Prekallikrein is homologous to factorXI, and similarly consists of four apple domains...
Deficiency in factorXI is known to cause hemophilia C. Factor XIIa is another plasma protein that is involved in the activation of zymogen factor is activated...
diagnosis for this inherited condition is the following: haemophilia A, factorXI deficiency, von Willebrand disease, fibrinogen disorders and Bernard–Soulier...
Factor IX (EC 3.4.21.22), also known as Christmas factor, is one of the serine proteases involved in coagulation; it belongs to peptidase family S1. Deficiency...
of coagulation, under development by Anthos Therapeutics. It is anti-factorXI antibody. Medicine portal Antibody Monoclonal antibody Immunology Verhamme...
FXIIa can initiate the coagulation cascade by cleaving and activating factorXI (FXI), which leads to formation of a blood clot. Additionally, the CAS...
levels of factor VIII, factor IX, factorXI, fibrinogen and thrombin-activatable fibrinolysis inhibitor, and decreased levels of tissue factor pathway inhibitor...
months of life. In the blood coagulation pathway, thrombin acts to convert factorXI to XIa, VIII to VIIIa, V to Va, fibrinogen to fibrin, and XIII to XIIIa...
clotting factors or coagulation factors. Genetic disorders, such as hemophilia and Von Willebrand disease, can cause a reduction in clotting factors. Anticoagulants...
homocystinuria, hyperhomocysteinemia, high fibrinogen levels, high factor IX levels, and high factorXI levels are associated with increased risk. Other associated...
glycoproteins of the Trypanosoma parasite Tubulin Some clotting factors Factor XIFactor XIII Fibrinogen Some receptors Nuclear receptors G protein βγ-subunit...
aircraft prototype Trichlorofluoromethane, a refrigerant used before 1995 FactorXI, a clotting agent found in blood F11 (classification), a classification...
capable of generating plasmin from plasminogen: Kallikrein is homologous to factorXI and consists of four apple domains and one serine protease domain.[citation...
distinguish factor deficiencies from factor inhibitors, such as lupus anticoagulant, or specific factor inhibitors, such as antibodies directed against factor VIII...
activation pathway factors (factor VIII, factor IX, factorXI and factor XII). Lupus anticoagulant will also rarely cause a factor assay to give a result...
glucose-6-phosphate dehydrogenase deficiency, early-onset of dystonia, factorXI deficiency, and Gaucher's disease. The FDA also said that it intended...
\xi ={\frac {\hbar }{\sqrt {2m\mu }}}=15.574\,\mathrm {\mu m} \,,} which is our factor. Now, make use of the fact that ξ ∝ 1 m μ {\displaystyle \xi \propto...
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