This condition is inherited in an autosomal recessive manner.
Specialty
Hematology, medical genetics
Factor VII deficiency is a bleeding disorder characterized by a lack in the production of Factor VII (FVII) (proconvertin), a protein that causes blood to clot in the coagulation cascade. After a trauma factor VII initiates the process of coagulation in conjunction with tissue factor (TF/factor III) in the extrinsic pathway.[citation needed]
The condition may be inherited or acquired. It is the most common of the rare congenital coagulation disorders.[1]
^Guglielmo Mariani, Francesco Bernardi (2009). "Factor VII Deficiency". Semin. Thromb. Hemost. 35 (4): 400–406. doi:10.1055/s-0029-1225762. PMID 19598068.
and 26 Related for: Factor VII deficiency information
IX and X. The gene for factorVII is located on chromosome 13 (13q34). FactorVIIdeficiency (congenital proconvertin deficiency) is rare and inherited...
FactorVIIdeficiency is a bleeding disorder characterized by a lack in the production of FactorVII (FVII) (proconvertin), a protein that causes blood...
platelets, and the exposure of subendothelial platelet tissue factor to coagulation factorVII, which ultimately leads to cross-linked fibrin formation. Platelets...
factor IX with its cofactor, factor VIII in a complex known as intrinsic pathway; and factorVII with its cofactor, tissue factor in a complex known as extrinsic...
Kais are prone to developing juvenile cataracts, liver disease, factorVIIdeficiency and heart problems. Thyroid problems have also been observed. Due...
Other causes of reactive thrombocythemia include: post surgery, iron deficiency, drugs, and rebound effect after bone marrow suppression. Research suggests...
rises first, since the activated FactorVII is the first to "disappear." In later stages of deficiency, the other factors (which have longer half lives)...
distinguish factordeficiencies from factor inhibitors, such as lupus anticoagulant, or specific factor inhibitors, such as antibodies directed against factor VIII...
medical science, antithrombin deficiency, was identified in 1965, while the most common abnormalities (including factor V Leiden) were described in the...
hemophilia A) is a blood clotting disorder caused by a genetic deficiency in clotting factor VIII, thereby resulting in significant susceptibility to bleeding...
iliofemoral deep vein thrombosis, phlegmasia cerulea dolens and factorVIIdeficiency". BMJ Case Reports. 2016: bcr2016215078. doi:10.1136/bcr-2016-215078...
iliofemoral deep vein thrombosis, phlegmasia cerulea dolens and factorVIIdeficiency". BMJ Case Reports. 2016: bcr2016215078. doi:10.1136/bcr-2016-215078...
models, mutations within the promoter region of factor IX have an age-dependent phenotype. FactorsVII, IX, and X all play key roles in blood coagulation...
it should only be used in clinical trials or with patients with factorVIIdeficiency. A new product of this type (Cresilon Hemostatic Gel or CHG, Vetigel...
appear to decrease the mortality rate. In those without previous factorVIIdeficiency, its use is not recommended outside of trial situations. Other medications...
and X. Some versions also contain factorVII. It is used to treat and prevent bleeding in hemophilia B if pure factor IX is not available. It may also...
Hypoprothrombinemia is a rare blood disorder in which a deficiency in immunoreactive prothrombin (Factor II), produced in the liver, results in an impaired...
and confusion. In Western countries, chronic alcoholism is a risk factor for deficiency. Also at risk are older adults, persons with HIV/AIDS or diabetes...
bleeding. The PT evaluates coagulation factors I, II, V, VII and X, while the PTT evaluates coagulation factors I, II, V, VIII, IX, X, XI and XII. The...
Phosphofructokinase deficiency is a rare muscular metabolic disorder, with an autosomal recessive inheritance pattern. It may affect humans as well as...
splice site mutation in the human gene for plasma factorVII that causes severe plasma factorVIIdeficiency, bleeding disease, results from a 251 bp NUMT...
which a congenital deficiency has not been described. In addition to the membrane-bound tissue factor, soluble form of tissue factor was also found which...
intermediate. The presence of uncarboxylated proteins indicates a vitamin K deficiency. Carboxylation allows them to bind (chelate) calcium ions, which they...
deficiency of Factor VIII causes classic hemophilia A while deficiencies of Factor IX cause "Christmas disease"(hemophilia B). Antibodies to Factor VIII...