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Hypoprothrombinemia information


Hypoprothrombinemia
Other namesCongenital factor II deficiency[1]
This condition is inherited in an autosomal recessive manner.
SpecialtyHematology Edit this on Wikidata

Hypoprothrombinemia is a rare blood disorder in which a deficiency in immunoreactive prothrombin (Factor II), produced in the liver, results in an impaired blood clotting reaction, leading to an increased physiological risk for spontaneous bleeding. This condition can be observed in the gastrointestinal system, cranial vault, and superficial integumentary system, affecting both the male and female population. Prothrombin is a critical protein that is involved in the process of hemostasis, as well as illustrating procoagulant activities. This condition is characterized as an autosomal recessive inheritance congenital coagulation disorder affecting 1 per 2,000,000 of the population, worldwide, but is also attributed as acquired.

  1. ^ RESERVED, INSERM US14-- ALL RIGHTS. "Orphanet: Congenital factor II deficiency". www.orpha.net. Retrieved 5 June 2019.{{cite web}}: CS1 maint: numeric names: authors list (link)

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Hypoprothrombinemia

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