Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. The protein encoded by this gene is a member of the fibroblast growth...
lateral mesoderm, restricting the expression of FGF10 through intermediate Wnt signals. Then, FGF10 in the lateral plate mesoderm signals to the surface...
secretes FGF8 and FGF4 which maintains the FGF10 signal and induces proliferation in the mesoderm. The position of FGF10 expression is regulated by Wnt8c in...
mesoderm. WNT2B and WNT8C stabilize this FGF10 expression in the forelimb and hindlimb, respectively. This FGF10 expression stimulates WNT3 expression in...
and FGF4 which maintain the FGF10 signal and induce proliferation in the mesoderm.[citation needed] The position of FGF10 expression is regulated by two...
produce Fgf10. Fgf10 then signals to the ectoderm to begin production of Fgf8, which also stimulates the production of Fgf10. Deletion of Fgf10 results...
complex and regulated by a variety of mechanisms in a tissue specific manner. FGF10 is also known as "keratinocyte growth factor 2". Palifermin Rotolo S, Ceccarelli...
COPD. A genetic association for the variants has been sometimes found with FGF10. Alcohol abuse can lead to alcoholic lung disease and is seen to be an independent...
fibroblast growth factors FGF10 and FGFR2b, and bone morphogenetic protein BMP4. FGF10 is seen to have the most prominent role. FGF10 is a paracrine signalling...
Lana-Elola E, Rice DP, Sharpe J, Dickson C (February 2009). "Evidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrome mouse...
which are structurally related signaling molecules: Members FGF1 through FGF10 all bind fibroblast growth factor receptors (FGFRs). FGF1 is also known...
signaled locally by proteins known as fibroblast growth factors that include FGF10. The shoulder girdle in turtles is made up of two bones, the scapula and...
by research on animal models, including of the genes BMP4, SHH, SHOX2, FGF10 and MSX1. Environmental influences may also cause, or interact with genetics...
in the body is demonstrated in response to the signaling of the ramogen FGF10, serving as an inhibitor of branching. The following table is a list of...
development is signalled locally by fibroblast growth factors including FGF10. Zoologists have sought to explain the evolutionary origin of the turtles...
levels of fibroblast growth factor 8 (FGF8) and fibroblast growth factor 10 (FGF10). FGF8 in turn regulates a number of developmental processes, such as limb...
crucial in developmental and evolutionary elongation of bat forelimb digits.FGF10 signaling is also likely required for the development of bat wing membrane...
activate one or more of the FGFRs: FGF1 to FGF10 and FGF16 to FGF23. Fourteen of these, FGF1 to FGF6, FGF8, FGF10, FGF17, and FGF19 to FGF23 bind and activate...
BMP signals help control patterning in the early otic vesicle. Fgf3 and Fgf10 are suggested to play a role in otic induction in mice, as were Msx genes...
Lana-Elola E, Rice DP, Sharpe J, Dickson C (Feb 2009). "Evidence that Fgf10 contributes to the skeletal and visceral defects of an Apert syndrome mouse...
binding to the Patched receptor, and directly activating BMP2, Fgf10, Wnt5a, and BMP4. Fgf10 induces further Shh expression, while BMP4 represses Wnt5a expression...
distal limb structures. Sp8 and Sp9 mediate Fgf10 signaling, which in turn regulates Fgf8 expression (Fgf10→Fgf8). Fgf8 is essential for normal limb development...
substrates and downregulation of fibroblast growth factor 8 (FGF8) and FGF10. This disrupts the positive feedback loop between the two growth factors...
; Thiery, J. P.; Czernichow, P.; Bellusci, S.; Scharfmann, R. (2001). "Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor...