In molecular biology, the term extrinsic pathway may refer to multiple cascades of protein interactions.
The extrinsic pathway of apoptosis refers to cell death induced by external factors that activate the death-inducing signaling complex.
The extrinsic pathway of blood coagulation is also known as the tissue factor pathway and refers to a cascade of enzymatic reactions resulting in blood clotting and is done with the addition of injured tissue cells.
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a number of extracurricular molecules is specialised to induce apoptosis.These extracurricular signals molecules bind with cell surface receptors (termed death receptors).
molecular biology, the term extrinsicpathway may refer to multiple cascades of protein interactions. The extrinsicpathway of apoptosis refers to cell...
mechanisms are the intrinsic pathway (also called the mitochondrial pathway) and the extrinsicpathway. The intrinsic pathway is activated by intracellular...
normalized ratio (INR) – is an assay for evaluating the extrinsicpathway and common pathway of coagulation. This blood test is also called protime INR...
potential pathways that may be followed when apoptosis is needed. There is the extrinsicpathway and the intrinsic pathway. Both pathways involve the...
activation of factor X—the tissue factor pathway. In doing so, it has replaced the previously named extrinsicpathway in order to eliminate ambiguity. The...
coagulation inhibitor: the factor Xa dependent inhibitor of the extrinsicpathway of coagulation". Biochemistry. 30 (6): 1571–7. doi:10.1021/bi00220a018...
(PT). The PT measures the speed of clotting by means of the extrinsicpathway and common pathway. Partial thromboplastin time is typically analyzed by a medical...
tissue factor, both of which are needed in the activation of the extrinsicpathway. However, partial thromboplastin is just phospholipids, and not tissue...
categorized in two: extrinsic and intrinsic pathways. The extrinsicpathway are directly induced upon renal ischemic injury, while intrinsic pathways are dependent...
Apoptosis can be triggered through two main pathways; extrinsic and intrinsic pathways. The extrinsicpathway mostly involves extracellular signals triggering...
complex known as intrinsic pathway; and factor VII with its cofactor, tissue factor in a complex known as extrinsicpathway. It is therefore the first...
activity in factors of both the intrinsic pathway (F-IX) which is monitored by PTT, as well as the extrinsicpathway (F-VII) which is monitored by PT. However...
The visual pathway consists of structures that carry visual information from the retina to the brain. Lesions in that pathway cause a variety of visual...
derived measures of prothrombin ratio (PR) and INR are measures of the extrinsicpathway of coagulation. This test is also called "ProTime INR" and "INR PT"...
to 4 hours. Inhibition of Factor Xa interrupts the intrinsic and extrinsicpathway of the blood coagulation cascade, inhibiting both thrombin formation...
copy. In these individuals, activated factor VII, a protein in the extrinsicpathway of the coagulation cascade, can be infused as a treatment for haemorrhage...
transferase, cholesterol, and prothrombin time (i.e. coagulation via the extrinsicpathway took longer), and fewer platelets. Normally, joint cartilages have...
commonly seen in EVD has been attributed to increased activation of the extrinsicpathway of the coagulation cascade due to excessive tissue factor production...
proteolytic caspase cascade that emanates from either an extrinsic or an intrinsic pathway. The extrinsicpathway is initiated by membrane bound death receptors...
activation of factor X is a common point between the intrinsic and extrinsicpathway of blood coagulation. Activated factor X (FXa) is the sole enzyme...
Excessive ROS can induce apoptosis through both the extrinsic and intrinsic pathways. In the extrinsicpathway of apoptosis, ROS are generated by Fas ligand...
coagulation in conjunction with tissue factor (TF/factor III) in the extrinsicpathway.[citation needed] The condition may be inherited or acquired. It is...
pleasurable. Extrinsic rewards derive their motivational value as a result of a learned association (i.e., conditioning) with intrinsic rewards. Extrinsic rewards...
or damage-associated molecular patterns (DAMPs) by activating the extrinsicpathway of coagulation. Neutrophils facilitate the blood coagulation by NETosis...
pressure-, which eventually causes cell membrane rupture. The apoptotic extrinsicpathway starts with the formation of the TNFR-1 complex-I, which contains...
activation of Factor X to Xa initiates the coagulation cascade’s common pathway, leading to clot formation at the site of hemorrhage. Activated FVII binds...
and then cleaved by factor XIa (of the contact pathway) or factor VIIa (of the tissue factor pathway) to produce a two-chain form, where the chains are...
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