In enzymology, an ethanolamine kinase (EC 2.7.1.82) is an enzyme that catalyzes the chemical reaction
ATP + ethanolamine ADP + O-phosphoethanolamine
Thus, the two substrates of this enzyme are ATP and ethanolamine, whereas its two products are ADP and O-phosphoethanolamine.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:ethanolamine O-phosphotransferase. Other names in common use include ethanolamine kinase (phosphorylating), and ethanolamine phosphokinase. This enzyme participates in glycerophospholipid metabolism.
and 22 Related for: Ethanolamine kinase information
In enzymology, an ethanolaminekinase (EC 2.7.1.82) is an enzyme that catalyzes the chemical reaction ATP + ethanolamine ⇌ {\displaystyle \rightleftharpoons...
enzyme in mammalian tissue. A related enzyme, ethanolaminekinase, tends to co-purify with choline kinase leading to a suggestion that the two activities...
UCSC Genome Browser. Spanner S, Ansell GB (1979). "Choline kinase and ethanolaminekinase activity in the cytosol of nerve endings from rat forebrain"...
AstraZeneca. It acts as a dual kinase inhibitor, with selective actions as a Src inhibitor and a Bcr-Abl tyrosine-kinase inhibitor. It was originally under...
prototype of the benzodiazepine Diphenhydramine (Benadryl) is the prototype ethanolamine antihistamine Nifedipine is the prototype dihydropyridine calcium channel...
sphingosine backbone is O-linked to a (usually) charged head group such as ethanolamine, serine, or choline.[citation needed] The backbone is also amide-linked...
Choline is the parent compound of the cholines class, consisting of ethanolamine residue having three methyl groups attached to the same nitrogen atom...
receptor modulator (SERM) of the triphenylethylene group as well as a protein kinase C (PKC) inhibitor. It is under development for the treatment of estrogen...
myelofibrosis. It is a macrocyclic protein kinase inhibitor. It mainly inhibits Janus kinase 2 (JAK2) and Fms-like tyrosine kinase 3\CD135 (FLT3). Common side effects...
Remibrutinib is a small molecule drug that acts as a Bruton's tyrosine kinase (BTK) inhibitor. It is in development for the treatment of chronic spontaneous...
capsules that are taken by mouth. It is a semi-selective inhibitor of Janus kinase 2 (JAK-2). It was approved by the FDA on 16 August 2019. Myelofibrosis is...
involving a lipid messenger that binds a protein target, such as a receptor, kinase or phosphatase, which in turn mediate the effects of these lipids on specific...
endoplasmic reticulum. Both reactions require a serine but product an ethanolamine or choline, respectively. These are promoted by phosphatidylserine synthase...
Tofacitinib Baillache DJ, Unciti-Broceta A. Recent developments in anticancer kinase inhibitors based on the pyrazolo[3,4-d]pyrimidine scaffold. RSC Med Chem...
PMC 1187734. PMID 5801671. Jenkins, BT, Hajra, AK (1976). "Glycerol Kinase and Dihydroxyacetone Kinase in Rat Brain" (PDF). Journal of Neurochemistry. 26 (2): 377–385...
the inclusion of an oxymethylene group (-O-CH2-) between the aryl and ethanolamine moieties of pronethalol, greatly increasing the potency of the compound...
PMID 4898381. Del Papa MF, Perego M (November 2008). "Ethanolamine activates a sensor histidine kinase regulating its utilization in Enterococcus faecalis"...
hydrolase (FAAH), which cleaves anandamide into arachidonic acid and ethanolamine or monoacylglycerol lipase (MAGL), and 2-AG into arachidonic acid and...
posttranslationally modified by novel amide-linked ethanolamine-phosphoglycerol moieties. Addition of ethanolamine-phosphoglycerol to specific glutamic acid residues...
literature describes the synthesis of glycocyamine by catalytic oxidation of ethanolamine to glycine and subsequent reaction with cyanamide in aqueous solution...
activation, preventing CB1 mediated changes to mitogen-activated protein kinase (MAPK) phosphorylation but without affecting the signalling mediated by...
Global Information