Establishment of sister chromatid cohesion information
Sister chromatid cohesion refers to the process by which sister chromatids are paired and held together during certain phases of the cell cycle. Establishment of sister chromatid cohesion is the process by which chromatin-associated cohesin protein becomes competent to physically bind together the sister chromatids. In general, cohesion is established during S phase as DNA is replicated, and is lost when chromosomes segregate during mitosis and meiosis. Some studies have suggested that cohesion aids in aligning the kinetochores during mitosis by forcing the kinetochores to face opposite cell poles.[1]
^Wang, Zhenghe; Christman, Michael F. (2001). "Replication-Related Activities Establish Cohesion Between Sister Chromatids". Cell Biochemistry and Biophysics. 35 (3): 289–301. doi:10.1385/cbb:35:3:289. PMID 11894848. S2CID 12433941.
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held together during certain phases of the cell cycle. Establishmentofsisterchromatidcohesion is the process by which chromatin-associated cohesin protein...
protein complex that mediates sisterchromatidcohesion, homologous recombination, and DNA looping. Cohesin is formed of SMC3, SMC1, SCC1 and SCC3 (SA1...
ends of the cells, while the cohesion between the sisterchromatids opposes this force. At the metaphase to anaphase transition, this cohesion between...
Bluetooth protocol for transmitting voice data ESCO1, or establishmentofsisterchromatidcohesion N-acetyltransferase 1, a protein that in humans is encoded...
acetyltransferase activity and may be required for the establishmentofsisterchromatidcohesion during the S phase of the cell cycle. Mutations in the ESCO2 gene...
involved in sisterchromatidcohesion. rad21 was first cloned by Birkenbihl and Subramani in 1992 by complementing the radiation sensitivity of the rad21-45...
Wang X, et al. (2007). "The DNA helicase ChlR1 is required for sisterchromatidcohesion in mammalian cells". J. Cell Sci. 119 (Pt 23): 4857–65. doi:10...
apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sisterchromatids between daughter cells. It is referred...
associated with duplicated chromatids in eukaryotic cells where the spindle fibers attach during cell division to pull sisterchromatids apart. The kinetochore...
In vertebrates, sisterchromatidcohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in...
our understanding of the cell cycle. He has made major contributions to our understanding of the mechanisms ofsisterchromatidcohesion, and their relationship...
characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sisterchromatidcohesionestablishment". J Biol...
characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sisterchromatidcohesionestablishment". The Journal...
characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sisterchromatidcohesionestablishment". The Journal...
position of the centromere on each chromosome, determining the position of kinetochore assembly and the final site ofsisterchromatidcohesion during mitosis...
centromeric sister-chromatidcohesion through Shugoshin during mitosis". Proceedings of the National Academy of Sciences of the United States of America....
protein that in humans is encoded by the NDC80 gene. Ndc80 is one of the proteins of outer kinetochore. It forms a heterotetramer with proteins NUF2, SPC25...
degrades mitotic cyclins, chromosomal proteins that maintain cohesionofsisterchromatids, and anaphase inhibitors. Abnormal spindle (Asp), a Polo kinase...
required for all of these processes. Consistently, inactivation of Nipbl results in the loss topologically associating domains and cohesion. NIPBL binds dynamically...
protein that in humans is encoded by the NDE1 gene. Mutations in both copies of NDE1 cause microlissencephaly type 4. ENSG00000275911 GRCh38: Ensembl release...
subunit of the intracellular Ib isoform of platelet-activating factor acetylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the...
humans is encoded by the ZW10 gene. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during...
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