DCC1 information

DSCC1
Identifiers
Aliases	DSCC1, DCC1, DNA replication and sister chromatid cohesion 1
External IDs	OMIM: 613203; MGI: 1919357; HomoloGene: 5464; GeneCards: DSCC1; OMA:DSCC1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	119,855,894 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	54,953,887 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; gonad; ; parotid gland; ; testicle; ; buccal mucosa cell; ; ventricular zone; ; embryo; ; ganglionic eminence; ; hair follicle; ; tendon of biceps brachii;
	Top expressed in
	hand; ; ureter; ; otic vesicle; ; primary oocyte; ; endocardial cushion; ; abdominal wall; ; vas deferens; ; medial ganglionic eminence; ; seminiferous tubule; ; spermatid;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; single-stranded DNA helicase activity; DNA binding; DNA clamp loader activity;
Cellular component	nucleoplasm; nucleus; chromosome, centromeric region; chromatin; Ctf18 RFC-like complex;
Biological process	maintenance of mitotic sister chromatid cohesion; cell cycle; DNA replication; regulation of DNA replication; post-translational protein acetylation; positive regulation of DNA-directed DNA polymerase activity; mitotic sister chromatid cohesion;
	Sources:Amigo / QuickGO
Orthologs
	79075
	72107
	ENSG00000136982
	ENSMUSG00000022422
	Q9BVC3
	Q14AI0
	NM_024094
	NM_183089; NM_001355594
	NP_076999
	NP_898912; NP_001342523
	Wikidata
View/Edit Human	View/Edit Mouse

Sister chromatid cohesion protein DCC1 is a protein that in humans is encoded by the DSCC1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136982 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022422 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Merkle CJ, Karnitz LM, Henry-Sánchez JT, Chen J (Aug 2003). "Cloning and characterization of hCTF18, hCTF8, and hDCC1. Human homologs of a Saccharomyces cerevisiae complex involved in sister chromatid cohesion establishment". The Journal of Biological Chemistry. 278 (32): 30051–6. doi:10.1074/jbc.M211591200. PMID 12766176.
^ "Entrez Gene: DCC1 defective in sister chromatid cohesion homolog 1 (S. cerevisiae)".

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