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CENPA information


CENPA
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCENPA, CENP-A, CenH3, centromere protein A
External IDsOMIM: 117139; MGI: 88375; HomoloGene: 1369; GeneCards: CENPA; OMA:CENPA - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001809
NM_001042426

NM_007681
NM_001302129
NM_001302130
NM_001302131
NM_001302132

RefSeq (protein)

NP_001035891
NP_001800

NP_001289058
NP_001289059
NP_001289060
NP_001289061
NP_031707

Location (UCSC)Chr 2: 26.76 – 26.8 MbChr 5: 30.82 – 30.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene.[5] CENPA is a histone H3 variant which is the critical factor determining the kinetochore position(s) on each chromosome[6] in most eukaryotes including humans.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000115163 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029177 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ EntrezGene 1058
  6. ^ Allshire RC, Karpen GH (December 2008). "Epigenetic regulation of centromeric chromatin: old dogs, new tricks?". Nature Reviews. Genetics. 9 (12): 923–937. doi:10.1038/nrg2466. PMC 2586333. PMID 19002142.

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CENPA

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Centromere protein A, also known as CENPA, is a protein which in humans is encoded by the CENPA gene. CENPA is a histone H3 variant which is the critical...

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Mutares

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US-based SPX Corporation in December 2016. Cenpa is a manufacturer of cardboard made from waste paper. Cenpa is an independent producer of cardboard, and...

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Neocentromere

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of CENPA deposition in S. pombe determine when CENPA is deposited, namely S phase and G2. In Arabidopsis thaliana, experiments suggest that CENPA deposition...

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Histone

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specific functions of the chromatin metabolism. For example, histone H3-like CENPA is associated with only the centromere region of the chromosome. Histone...

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Retrocausality

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(April 2014), "Status of Nonlocal Quantum Communication Test" (PDF), UW CENPA Annual Report 2013-14, Article 7.1, retrieved September 21, 2016. Frankel...

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List of human transcription factors

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ENSG00000115816 Unknown Known motif – In vivo/Misc source [100] DSTSATTGGCT CENPA ENSG00000115163 Unknown Likely sequence specific TF according to literature...

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Axion Dark Matter Experiment

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Sited at the Center for Experimental Nuclear Physics and Astrophysics (CENPA) at the University of Washington, ADMX is a large collaborative effort with...

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Centromere

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the chromosome. In holocentric chromosomes centromeric proteins, such as CENPA (CenH3) are spread over the whole chromosome. The nematode, Caenorhabditis...

Word Count : 3779

Wormholes in fiction

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August 2008 – via Center for Experimental Nuclear Physics and Astrophysics (CENPA) - University of Washington. Wolf, Mark J. P. (2012). Building Imaginary...

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Zap Energy

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Plasmas 28.11 (2021): 112509. https://doi.org/10.1063/5.0066257 Center. CENPA Seminar - Yue Zhang - Sustained Neutron Production from a Sheared-Flow-Stabilized...

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Nucleosome

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activate genes and regulatory elements) and in centromeres H3 is replaced by CENPA. A number of distinct reactions are associated with the term ATP-dependent...

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INCENP

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(or transiently interacting) proteins. The constitutive proteins include CENPA (centromere protein A), CENPB, CENPC1, and CENPD. The term 'passenger proteins'...

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Kinetochore

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disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice". Proceedings of the National Academy of Sciences of the United...

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Centromere protein B

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2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc". Human Molecular Genetics. 11 (19): 2319–29...

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Histone variants

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histone H3 variants are H3.3 and centromeric H3 variant (cenH3, called also CENPA in humans). Well studied species specific variants include H3.1, H3.2, TS...

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PARP2

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2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc". Human Molecular Genetics. 11 (19): 2319–29...

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BUB3

Last Update:

Saffery R, Wong LH, Kalitsis P, Choo KH (July 2002). "Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and...

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Ateliers de construction de La Meuse

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Between 1903 and 1957 Mines d'Auchel (Département Pas-de-Calais), later CENPA (in Bègles). Preserved at Ecomusée de la Grande Lande in Marquèze. 1971...

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