Global Information Lookup Global Information

NDC80 information


NDC80
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hskinetochore complex component, NDC80 kinetochore complex component
External IDsOMIM: 607272; MGI: 1914302; HomoloGene: 38141; GeneCards: NDC80; OMA:NDC80 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006101

NM_023294

RefSeq (protein)

NP_006092

NP_075783

Location (UCSC)Chr 18: 2.57 – 2.62 MbChr 17: 71.8 – 71.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene.[5][6][7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000080986 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024056 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chen Y, Riley DJ, Chen PL, Lee WH (October 1997). "HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis". Molecular and Cellular Biology. 17 (10): 6049–56. doi:10.1128/mcb.17.10.6049. PMC 232454. PMID 9315664.
  6. ^ Martin-Lluesma S, Stucke VM, Nigg EA (September 2002). "Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2". Science. 297 (5590): 2267–70. Bibcode:2002Sci...297.2267M. doi:10.1126/science.1075596. PMID 12351790. S2CID 7879023.
  7. ^ "Entrez Gene: NDC80 NDC80 homolog, kinetochore complex component (S. cerevisiae)".

and 18 Related for: NDC80 information

Request time (Page generated in 0.5388 seconds.)

NDC80

Last Update:

Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene. Ndc80 is one of the proteins of outer kinetochore. It forms...

Word Count : 1178

Kinetochore

Last Update:

in yeast revealed the relevance of the Ndc80 complex in kMTs anchoring. In Saccharomyces cerevisiae, the Ndc80 complex has four components: Ndc80p, Nuf2p...

Word Count : 7839

2700099C18Rik

Last Update:

NDC80 homolog, kinetochore complex component pseudogene is a protein that in humans is encoded by the 2700099C18Rik gene. "Entrez Gene: NDC80 homolog...

Word Count : 42

Chromosome 17

Last Update:

see the link in the infobox on the right. 2700099C18Rik: encoding protein NDC80 homolog, kinetochore complex component pseudogene ABI3: encoding protein...

Word Count : 1920

Iain Cheeseman

Last Update:

demonstrated a critical and direct role for a protein complex called Ndc80 (coded for by the gene NDC80) in directly associating with microtubules. Because many cancers...

Word Count : 518

SPC24

Last Update:

Information, U.S. National Library of Medicine. "Entrez Gene: SPC24 SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)". Nousiainen M, Silljé...

Word Count : 370

Trisha Davis

Last Update:

Davis, Trisha N; Asbury, Charles L (2019-05-02). "Tight bending of the Ndc80 complex provides intrinsic regulation of its binding to microtubules". eLife...

Word Count : 963

Protein filament

Last Update:

These microtubules will attach to the kinetochore at their positive end. NDC80 is a protein found at this binding point that will help with the stabilization...

Word Count : 1806

KNOP1

Last Update:

protein. DUF5595 is found in Nude C 80 (Ndc80) proteins which can be found in species such as Homo sapiens. Ndc80 protein complexes are a core component...

Word Count : 909

Spindle checkpoint

Last Update:

of the microtubule-severing KINI kinesin MCAK, the DASH complex, and the Ndc80/Hec1 complex at the microtubule-kinetochore interface. The Aurora-B/Ipl1...

Word Count : 9149

NUF2

Last Update:

1007/s004120100153. PMID 11685532. S2CID 22443613. "Entrez Gene: NUF2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)". DeLuca JG, Moree...

Word Count : 945

Carpediemonas

Last Update:

subunits, a microtubule plus-end tracking complex and all subunits of the Ndc80 complex involved in chromosome segregation. ORC and Cdc6 are proteins in...

Word Count : 1523

Andrea Musacchio

Last Update:

kinase Aurora B, Mps1 and Haspin in mitosis. In 2008, the structure of the Ndc80 complex set the foundation of a new line of his investigations on kinetochore...

Word Count : 1151

KNL1

Last Update:

kinetochore. It is a part of KMN network of proteins together with MIS12, and NDC80. KNL1 is involved in microtubule attachment to chromosome centromeres and...

Word Count : 963

NEK2

Last Update:

encoded by the NEK2 gene. NEK2 has been shown to interact with MAPK1 and NDC80. Protein kinase which is involved in the control of centrosome separation...

Word Count : 1182

FAM98A

Last Update:

200-256. Phyre2 found the most similar protein to be the human protein NDC80 kinetochore complex component, a nuclear protein that binds to microtubules...

Word Count : 2448

PSMC2

Last Update:

central channels in the CP alpha ring. PSMC2 has been shown to interact with: NDC80, PSMC1, PSMC4, and PSMD5. GRCh38: Ensembl release 89: ENSG00000161057 –...

Word Count : 2572

MIS12

Last Update:

shown to interact with NSL1, ZWINT, CASC5, Polyamine-modulated factor 1, NDC80, DSN1 and CBX5. GRCh38: Ensembl release 89: ENSG00000167842 – Ensembl, May...

Word Count : 649

PDF Search Engine © AllGlobal.net