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Drug antagonism information


Drug antagonism refers to a medicine stopping the action or effect of another substance, preventing a biological response.[1] The stopping actions are carried out by four major mechanisms, namely chemical, pharmacokinetic, receptor and physiological antagonism.[1] The four mechanisms are widely used in reducing overstimulated physiological actions. Drug antagonists can be used in a variety of medications, including anticholinergics, antihistamines, etc. The antagonistic effect can be quantified by pharmacodynamics. Some can even serve as antidotes for toxicities and overdose.

  1. ^ a b "Combined Effects of Drugs: Antagonism | Pharmacology | JoVE". www.jove.com. Retrieved 2024-04-08.

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Drug antagonism

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Drug antagonism refers to a medicine stopping the action or effect of another substance, preventing a biological response. The stopping actions are carried...

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drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist. Antagonist drugs interfere...

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most dissociatives' main mechanism of action being tied to NMDA receptor antagonism, some of these substances, which are nonselective in action and affect...

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interactions with other drugs: Analgesics: increased risk of kidney damage (nephrotoxicity) with nonsteroidal anti-inflammatory drugs; antagonism of diuretic effect...

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agonism, MT3 receptor antagonism, and sigma receptor agonism thought to have some involvement. Bromantane is a stimulant drug with anxiolytic properties...

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CALCRL

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dopamine D2 receptor antagonism and slow receptor dissociation kinetics. It has effects similar to the phenothiazines. The drug binds preferentially to...

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10- to 38-fold selectivity for 5-HT3 antagonism over activities at the other serotonin receptors. 5-HT3 antagonism appears to have a better effect on REM...

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antipsychotic activity is unknown. It may involve antagonism of dopamine and serotonin receptors. Antagonism of dopamine receptors is associated with extrapyramidal...

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