Annexin A4 information

ANXA4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ZOC
Identifiers
Aliases	ANXA4, ANX4, HEL-S-274, PIG28, ZAP36, P32.5, PAP-II, PP4-X, annexin A4
External IDs	OMIM: 106491; MGI: 88030; HomoloGene: 68164; GeneCards: ANXA4; OMA:ANXA4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	69,827,112 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	86,770,566 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; gallbladder; ; jejunal mucosa; ; duodenum; ; body of pancreas; ; mucosa of ileum; ; islet of Langerhans; ; bronchial epithelial cell; ; mucosa of colon; ; mucosa of sigmoid colon;
	Top expressed in
	Paneth cell; ; jejunum; ; crypt of lieberkuhn of small intestine; ; gastric mucosa; ; epithelium of stomach; ; ileum; ; pyloric antrum; ; mucous cell of stomach; ; migratory enteric neural crest cell; ; epithelium of small intestine;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	phospholipase inhibitor activity; calcium ion binding; calcium-dependent protein binding; NF-kappaB binding; protein binding; identical protein binding; calcium-dependent phospholipid binding; heparin binding; chondroitin sulfate binding;
Cellular component	cytoplasm; nuclear membrane; vesicle membrane; plasma membrane; cell surface; perinuclear region of cytoplasm; extracellular exosome; nucleus; cytosol; collagen-containing extracellular matrix;
Biological process	Notch signaling pathway; epithelial cell differentiation; regulation of transcription by RNA polymerase II; negative regulation of apoptotic process; negative regulation of NF-kappaB transcription factor activity; signal transduction; negative regulation of catalytic activity;
	Sources:Amigo / QuickGO
Orthologs
	307
	11746
	ENSG00000196975
	ENSMUSG00000029994
	P09525
	P97429
	NM_001153; NM_001320698; NM_001320700; NM_001320702; NM_001365496
	NM_013471; NM_001331120
	NP_001144; NP_001307627; NP_001307629; NP_001307631; NP_001352425
	NP_001318049; NP_038499
	Wikidata
View/Edit Human	View/Edit Mouse

Annexin A4 is a protein that in humans is encoded by the ANXA4 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196975 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029994 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tait JF, Smith C, Frankenberry DA, Miao CH, Adler DA, Disteche CM (Feb 1992). "Chromosomal mapping of the human annexin IV (ANX4) gene". Genomics. 12 (2): 313–8. doi:10.1016/0888-7543(92)90379-7. PMID 1346776.
^ "Entrez Gene: ANXA4 annexin A4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000196975 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029994 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1346776-5] Tait JF, Smith C, Frankenberry DA, Miao CH, Adler DA, Disteche CM (Feb 1992). "Chromosomal mapping of the human annexin IV (ANX4) gene". Genomics. 12 (2): 313–8. doi:10.1016/0888-7543(92)90379-7. PMID 1346776.

[entrez-6] "Entrez Gene: ANXA4 annexin A4".

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