negative regulation of sequestering of calcium ion
response to calcium ion
calcium ion transmembrane transport
cellular response to lead ion
response to thyroid hormone
cellular response to gonadotropin-releasing hormone
regulation of flagellated sperm motility
negative regulation of prolactin secretion
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
308
11747
Ensembl
ENSG00000164111
ENSMUSG00000027712
UniProt
P08758
P48036
RefSeq (mRNA)
NM_001154
NM_009673
RefSeq (protein)
NP_001145
NP_033803
Location (UCSC)
Chr 4: 121.67 – 121.7 Mb
Chr 3: 36.5 – 36.53 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Annexin A5 (or annexin V) is a cellular protein in the annexin group. In flow cytometry, annexin V is commonly used to detect apoptotic cells by its ability to bind to phosphatidylserine, a marker of apoptosis when it is on the outer leaflet of the plasma membrane. The function of the protein is unknown; however, annexin A5 has been proposed to play a role in the inhibition of blood coagulation by competing for phosphatidylserine binding sites with prothrombin and also to inhibit the activity of phospholipase A1. These properties have been found by in vitro experiments.
^ abcGRCh38: Ensembl release 89: ENSG00000164111 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000027712 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
AnnexinA5 (or annexin V) is a cellular protein in the annexin group. In flow cytometry, annexin V is commonly used to detect apoptotic cells by its ability...
and fungi). In humans, the annexins are found inside the cell. However some annexins (Annexin A1, Annexin A2, and AnnexinA5) can be secreted from the...
biology, an annexinA5 affinity assay is a test to quantify the number of cells undergoing apoptosis. The assay uses the protein annexinA5 to tag apoptotic...
A5 and variants may refer to: A5 regulatory sequence in biochemistry A5, the abbreviation for the androgen Androstenediol AnnexinA5, a human cellular...
against protein S and annexinA5. Protein S is a co-factor of protein C, which is one of the body's own anti-clotting factors. AnnexinA5 forms a shield around...
concept for the therapy is based on the anti-inflammatory properties of AnnexinA5, a body own protective protein that acts simultaneously against several...
Annexin A1, also known as lipocortin I, is a protein that is encoded by the ANXA1 gene in humans. Annexin A1 belongs to the annexin family of Ca2+-dependent...
Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. Annexin 2 is involved in diverse cellular processes such...
perform quantification of markers by maintaining the spatial context. AnnexinA5 affinity assay, a test for cells undergoing apoptosis, often uses flow...
with each range defined); b) biochemical composition (CD63+/CD81+- EVs, AnnexinA5-stained EVs, etc.); or c) descriptions of conditions or cell of origin...
chromosome 4 by CCNA2, a gene encoding for cyclin A2, and ANXA5, which encodes annexinA5. It is also neighbored by PP12613 located on the positive strand. The...
Kinase insert domain receptor has been shown to interact with SHC2, AnnexinA5 and SHC1. Cluster of differentiation VEGF receptors GRCh38: Ensembl release...
the ITGB5 gene. Integrin, beta 5 has been shown to interact with PTK2, AnnexinA5 and PAK4. ITGB5 encodes a subunit of integrin that can interact with several...
further research and development, Jaffee has hopes to make the protein, Annexin A2, not as overworked to prevent the advancement of pancreatic cancer in...
Brancaleone V, Bena S, Perretti M (November 2011). "Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear...
calcium-binding proteins, called EF hand proteins. The other group, called annexins, bind calcium and phospholipids such as lipocortin. Many other proteins...
Global Information
