The S100 proteins are a family of low molecular-weight proteins found in vertebrates characterized by two calcium-binding sites that have helix-loop-helix ("EF-hand-type") conformation. At least 21 different S100 proteins are known.[1] They are encoded by a family of genes whose symbols use the S100 prefix, for example, S100A1, S100A2, S100A3.
They are also considered as damage-associated molecular pattern molecules (DAMPs), and knockdown of aryl hydrocarbon receptor downregulates the expression of S100 proteins in THP-1 cells.[2]
^Marenholz I, Heizmann CW, Fritz G (2004). "S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature)". Biochemical and Biophysical Research Communications. 322 (4): 1111–22. doi:10.1016/j.bbrc.2004.07.096. PMID 15336958.
^Memari B, Bouttier M, Dimitrov V, Ouellette M, Behr MA, Fritz JH, White JH (2015). "Engagement of the Aryl Hydrocarbon Receptor in Mycobacterium tuberculosis-Infected Macrophages Has Pleiotropic Effects on Innate Immune Signaling". Journal of Immunology. 195 (9): 4479–91. doi:10.4049/jimmunol.1501141. PMID 26416282.
The S100proteins are a family of low molecular-weight proteins found in vertebrates characterized by two calcium-binding sites that have helix-loop-helix...
S100 or S-100 may refer to: S-100 bus, an early computer bus S-100, an International Hydrographic Organization standard S100protein, low-molecular-weight...
S100 calcium-binding protein B (S100B) is a protein of the S100protein family. S100proteins are localized in the cytoplasm and nucleus of a wide range...
ProteinS100-A4 (S100A4) is a protein that in humans is encoded by the S100A4 gene. The protein encoded by this gene is a member of the S100 family of...
S100 calcium-binding protein A9 (S100A9) also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B is a protein that in humans...
families: the cornified envelope precursor family, the S100protein family and the S100 fused type protein (SFTP) family. It has been hypothesized that the...
ProteinS100-A1, also known as S100 calcium-binding protein A1 is a protein which in humans is encoded by the S100A1 gene. S100A1 is highly expressed...
S100 calcium-binding protein A12 (S100A12) is a protein that in humans is encoded by the S100A12 gene. Human S100A12, also known as calgranulin C, was...
Calcium-binding protein Calcium-binding protein 1 S100 calcium-binding protein A1 TATA-binding protein Actin-binding protein Most actin binding proteins bind on...
S100 calcium-binding protein A8 (S100A8) is a protein that in humans is encoded by the S100A8 gene. It is also known as calgranulin A. The proteins S100A8...
Calprotectin is a complex of the mammalian proteins S100A8 and S100A9. Other names for calprotectin include MRP8-MRP14, calgranulin A and B, cystic fibrosis...
S100 calcium-binding protein A10 (S100A10), also known as p11, is a protein that is encoded by the S100A10 gene in humans and the S100a10 gene in other...
sinonasal tract associated with overlying respiratory epithelium and showing S100protein and actin immunoreactivity The tumor often affects multiple sites within...
M (May 1998). "Prognostic significance of p53, bcl-2, vimentin, and S100protein-positive Langerhans cells in endometrial carcinoma". Human Pathology...
tumor: immunohistochemical assessment of inhibin-alpha, protein gene product 9.5, S100protein, CD68, and Ki-67 proliferative index with clinical correlation"...
like biopsy or imaging. Tumor markers can be proteins, carbohydrates, receptors and gene products. Proteins include hormones and enzymes. To detect enzyme...
precursor protein during terminal differentiation of epidermal cells. In humans, profilaggrin is encoded by the FLG gene, which is part of the S100 fused-type...
S100 calcium-binding protein A11 (S100A11) is a protein that in humans is encoded by the S100A11 gene. The protein encoded by this gene is a member of...
antifungal protein S100A7, which is not a member of this protein family. Instead, S100A7 belongs in the S100protein family. The proteins kill fungi by...
S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene. S100A7 is a member of the...
PMID 20566001. Ichikawa H; Jacobowitz DM; Sugimoto T (February 1997). "S100protein-immunoreactive primary sensory neurons in the trigeminal and dorsal root...
S100 calcium-binding protein A3 (S100A3) is a protein that in humans is encoded by the S100A3 gene. The protein encoded by this gene is a member of the...
The S100 calcium-binding protein mS100a7a15 is the murine ortholog of human S100A7 (Psoriasin) and human S100A15 (Koebnerisin). mS100a7a15 is also known...
neoplastic cells are S100protein positive (approximately 80%), and show membrane and vacuole CD31 immunoreactivity. Uncoupling protein 1 (UCP1), a unique...
S100 calcium-binding protein G (S100G) is a protein that in humans is encoded by the S100G gene. This gene encodes calbindin D9K, a vitamin D-dependent...
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