Amobarbital (formerly known as amylobarbitone or sodium amytal as the soluble sodium salt) is a drug that is a barbiturate derivative. It has sedative-hypnotic properties. It is a white crystalline powder with no odor and a slightly bitter taste. It was first synthesized in Germany in 1923. It is considered a short to intermediate acting barbiturate.[citation needed]
If amobarbital is taken for extended periods of time, physiological and psychological dependence can develop. Amobarbital withdrawal mimics delirium tremens and may be life-threatening. Amobarbital was manufactured by Eli Lilly and Company in the US under the brand name Amytal in bright blue bullet shaped capsules (known as Pulvules) or pink tablets (known as Diskets)[2] containing 50, 100, or 200 milligrams of the drug. The drug was also manufactured generically.
Amobarbital was widely misused, known as "Blue Heavens" on the street. Amytal, as well as Tuinal, a combination drug containing equal quantities of secobarbital and amobarbital, were both manufactured by Eli Lilly until the late-1990s. However, as the popularity of benzodiazepines increased, prescriptions for these medications became increasingly rare beginning in the mid to late-1980s.
^Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^Winek, Charles L. (1965-02-01). "Dosage Form Names and Product Identification". American Journal of Health-System Pharmacy. 22 (2): 84. doi:10.1093/ajhp/22.2.82. ISSN 1079-2082.
Amobarbital (formerly known as amylobarbitone or sodium amytal as the soluble sodium salt) is a drug that is a barbiturate derivative. It has sedative-hypnotic...
The Wada test, also known as the intracarotid sodium amobarbital procedure (ISAP) or Wada-Milner Test, establishes cerebral language and memory representation...
combination drug composed of two barbiturate salts (secobarbital sodium and amobarbital sodium) in equal proportions. Tuinal was introduced as a sedative-hypnotic...
most commonly used are amobarbital (Amytal), pentobarbital (Nembutal), and secobarbital (Seconal). A combination of amobarbital and secobarbital (called...
psychiatrists in the post-World War II era. Also called sodium amytal interview, amobarbital interview, or amytal interview, it uses free association as well as dream...
3-quinuclidinyl benzilate, midazolam, flunitrazepam, sodium thiopental, and amobarbital, among others. Although a variety of such substances have been tested...
molecular formula C11H18N2O3 (molar mass: 226.27 g/mol) may be referred as: Amobarbital Pentobarbital Timoxeline Barbebutenol, a fictional drug in the film Johnny...
in the Drugs and Cosmetics Rules 1945: The list of Schedule X drugs: Amobarbital Amphetamine Barbital Cyclobarbital Dexamphetamine Ethchlorvynol Glutethimide...
Drinamyl in the UK) was a brand name combination drug composed of sodium amobarbital (previously called amylbarbitone and its brand name Amytal) and dextroamphetamine...
diazepam (Valium) or nitrazepam (Mogadon) and the barbiturates, such as amobarbital (Amytal) or secobarbital (Seconal) Other agents impacting the central...
refer to the terminally branched group also called isopentyl, as in amobarbital. A cyclopentyl group is a ring with the formula -C5H9. The name is also...
effects. Pentobarbital is synthesized by methods analogous to that of amobarbital, the only difference being that the alkylation of α-ethylmalonic ester...
furosemide, and hydrochlorothiazide have been known to interfere with amobarbital, which has led to inadequate anesthetization during the Wada test. Zonisamide...
known to be a stimulant. See also Antipsychotic controversy Barbiturates Amobarbital Benzylbutylbarbiturate Butalbital (Fioricet) Pentobarbital (Nembutal)...
The combination of clonazepam and certain barbiturates (for example, amobarbital), at prescribed doses has resulted in a synergistic potentiation of the...
to produce anesthesia or sedation, the most common are: Barbiturates Amobarbital (trade name: Amytal) Methohexital (trade name: Brevital) Thiamylal (trade...
Dexedrine, a stimulant, and Dexamyl, a stimulant-sedative; traces of amobarbital, an ingredient in Dexamyl, were found in his blood. The autopsy report...
39. An autopsy later showed a lethal combination of secobarbital and amobarbital, prescriptions for her insomnia and diet, which contributed to her death...
Jones-Gotman M, Sziklas V, Djordjevic J (August 2009). "Intracarotid amobarbital procedure and etomidate speech and memory test". The Canadian Journal...