Drug that reduces excitement without inducing sleep
"Tranquilizer" redirects here. For other uses, see Tranquilizer (disambiguation).
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Sedative
Drug class
NOVO-SED sedative in pills. Significantly cheaper analogue of Novo-Passit® (Novo-Passit®)
Clinical data
Drugs.com
Drug Classes
External links
MeSH
D006993
Legal status
In Wikidata
A sedative or tranquilliser[note 1] is a substance that induces sedation by reducing irritability[1] or excitement.[2] They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA). In spite of the fact that each sedative acts in its own way, most produce relaxing effects by increasing GABA activity.[3]
This group is related to hypnotics. The term sedative describes drugs that serve to calm or relieve anxiety, whereas the term hypnotic describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness) they are often referred to collectively as sedative-hypnotic drugs.[4]
Sedatives can be used to produce an overly-calming effect (alcohol being the most common sedating drug). In the event of an overdose or if combined with another sedative, many of these drugs can cause deep unconsciousness and even death.
Cite error: There are <ref group=note> tags on this page, but the references will not show without a {{reflist|group=note}} template (see the help page).
^"Johns Hopkins Colon Cancer Center - Glossary S". Archived from the original on 1 December 2017. Retrieved 1 January 2009.
^"sedative" at Dorland's Medical Dictionary
^"Sedatives | Psychology Today". Psychology Today. Retrieved 20 November 2017.
^Brunton, Laurence L.; Lazo, John S.; Lazo Parker, Keith L. (2006). "17: Hypnotics and Sedatives". Goodman & Gilman's The Pharmacological Basis of Therapeutics (11th ed.). The McGraw-Hill Companies, Inc. ISBN 978-0-07-146804-6. Retrieved 6 February 2014.
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain...
insomnia (sleeplessness). This group of drugs is related to sedatives. Whereas the term sedative describes drugs that serve to calm or relieve anxiety, the...
Methaqualone is a hypnotic sedative. It was sold under the brand names Quaalude (/ˈkweɪluːd/ KWAY-lood) and Sopor among others, which contained 300 mg...
Substances that may cause this toxidrome are opioids. The symptoms of sedative/hypnotic toxidrome include ataxia, blurred vision, coma, confusion, delirium...
of Sedative, hypnotic or anxiolytic Harmful pattern of use of Sedative, hypnotic or anxiolytic Sedative, hypnotic or anxiolytic dependence Sedative, hypnotic...
with a hypodermic needle and filled with a sedative, vaccine, or antibiotic. A dart gun containing a sedative is called a tranquillizer gun (also spelled...
name flakka and colloquially called the zombie drug Xylazine, a horse sedative used recreationally by itself or in combination with other drugs, also...
effects. They have been used recreationally for their anti-anxiety and sedative effects, and are thus controlled in most countries due to the risks associated...
is a geminal diol with the formula Cl3C−CH(OH)2. It was first used as a sedative and hypnotic in Germany in the 1870s. Over time it was replaced by safer...
as a sedative, analgesic, and muscle relaxant in dogs, cats, horses, elk, fallow deer, mule deer, sika deer, and white-tailed deer. The sedative and analgesic...
the thought of being sick. Many beneficial effects of lorazepam (e.g., sedative, muscle relaxant, anti-anxiety, and amnesic effects) may become adverse...
benzodiazepines of high potency or short half-life. Other cross-tolerant sedative hypnotics, such as barbiturates or alcohol, increase the risk of benzodiazepine...
differential diagnosis should include intoxication by other substances with sedative effects, such as benzodiazepines, anticonvulsants (carbamazepine), alcohols...
Diphenhydramine (DPH) is an antihistamine and sedative mainly used to treat allergies, insomnia, and symptoms of the common cold. It is also less commonly...
the United States. It possesses anaesthetic, anticonvulsant, anxiolytic, sedative, and hypnotic properties. In the United Kingdom, it was known as quinalbarbitone...
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure...
a sedative to treat severe insomnia.[unreliable medical source?] In addition to the hypnotic properties, triazolam's amnesic, anxiolytic, sedative, anticonvulsant...
of propofol to kick in, and effects last six minutes. Propofol has both sedative and amnestic effects, but provides no analgesia. Adverse effects to look...
Chlordiazepoxide, trade name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia...
other sedative-hypnotics such as zolpidem and zopiclone as well as opiates and illegal drugs is common in alcoholics. Alcohol itself is a sedative-hypnotic...
Phenergan among others, is a first-generation antihistamine, antipsychotic, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also...
Nervine was a patent medicine tonic with sedative effects introduced in 1884 by Dr. Miles Medical Company (later Miles Laboratories which was absorbed...
the Lactuca (lettuce) genus, often ingested for its mild analgesic and sedative effects. It is related to common lettuce (L. sativa), and is often called...
an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant...
names begin with the letter "z"), are a class of psychoactive; depressant, sedative, hyponotic, anxiolytic drugs that are benzodiazepine-like in uses, such...
as an antipsychotic, but is now almost exclusively used on animals as a sedative and antiemetic. A closely related analogue, chlorpromazine, is still used...
from the base of the stems. It is known as lettuce opium because of its sedative and analgesic properties. It has also been reported to promote a mild sensation...
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