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Tuinal information


Tuinal
structure
Combination of
secobarbitalshort-acting barbiturate
amobarbitalintermediate-acting barbiturate
Clinical data
Routes of
administration
oral

Tuinal was the brand name of a discontinued combination drug composed of two barbiturate salts (secobarbital sodium and amobarbital sodium) in equal proportions.

Tuinal was introduced as a sedative-hypnotic (sleeping pill) medication in the late 1940s by Eli Lilly. It was also used in obstetrics for childbirth.[1][2] It was produced in brightly colored half-reddish orange and half-turquoise blue gelatin capsule form (bullet-shaped Pulvules) for oral administration. Individual capsules contained 50 mg, 100 mg, or 200 mg of barbiturate salts. The combination of a short-acting barbiturate, Secobarbital, with an intermediate-acting barbiturate, Amobarbital, aimed to provide "a rapid yet prolonged hypnotic action".[3]

Eli Lilly has discontinued the manufacture of Tuinal in the United States due to the diminishing use of barbiturates (replaced by the benzodiazepine family of drugs) in outpatient treatment, and its widespread abuse.[4] Currently, Valleant Labs markets Secobarbital capsules only. Flynn Pharma of Ireland no longer manufactures Tuinal, Seconal or Amytal (amobarbital). Amytal has been discontinued, though sodium amytal injection form remains.

  1. ^ Waters AB (1947). "Pethidine In Labour". The British Medical Journal. 2 (4514): 71–72. doi:10.1136/bmj.2.4514.71-b. ISSN 0007-1447. JSTOR 20370143. PMC 2055200. PMID 20344014.
  2. ^ "Front Matter". The British Medical Journal. 1 (4539). 1948. ISSN 0007-1447. JSTOR 25361874.
  3. ^ "Front Matter". The American Journal of Nursing. 47 (5): 1–24. 1947. ISSN 0002-936X. JSTOR 3457169.
  4. ^ Mitchell M, Willingham EJ, Atkins WA (2012). Key K (ed.). The Gale Encyclopedia of Mental Health. Vol. 1 (3rd ed.). Detroit, MI: Gale eBooks. p. 171. ISBN 9781414490144. Retrieved November 4, 2022.

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Arthur Koestler

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their London home by swallowing lethal quantities of barbiturate-based Tuinal capsules. [Koestler] began his education in the twilight of the Austro-Hungarian...

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Gram Parsons

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emblazoned with all sorts of hippie accoutrements, including marijuana, Tuinal, and Seconal-inspired patches on Parsons' suit. Along with the Parsons-Hillman...

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Imogen Hassall

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Mombasa that day. She had apparently committed suicide by overdosing on Tuinal tablets. She was interred in Gap Road Cemetery, Wimbledon, London.[citation...

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secobarbital (Seconal). A combination of amobarbital and secobarbital (called Tuinal) is also highly used. Short-acting and intermediate-acting barbiturates...

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49 Poet, playwright Barbital Suicide Imogen Hassall 1942 1980 38 Actress Tuinal Unknown Bobby Hatfield 1940 2003 63 Musician Cocaine Unknown Drug-induced...

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Anthony Bourdain

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The Gilded Palace of Sin

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deep-green marijuana leaves on the front, and embroidered Seconal and Tuinal pills scattered elsewhere. Parsons asked that a flaming red cross surrounded...

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Get Your Wings

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was a mess, and I moved all the shit aside, put a rug down, popped three Tuinals, snorted some blow, sat down on the floor, tuned the guitar to that tuning...

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Sid Vicious

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a party in their hotel room, during which Vicious took approximately 30 Tuinal tablets, and while numerous people came and went, was comatose for the rest...

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Brian Epstein

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railway station, in Uckfield, instead of driving under the influence of Tuinal. Epstein replied that he would eat something, read his mail, and watch Juke...

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Pal Shazar

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collection of her short stories, Deliver Love, in 2017, and Volleyball on Tuinal, a collection of poems, in 2021. Shazar wrote a collection of songs based...

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Todd Storz

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intoxication. The drug in question was Tuinal, which was sometimes prescribed to insomniacs to help induce sleep. Tuinal was known to be dangerous because...

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which is the same concept but using opioids instead of a barbiturate. Tuinal, an insomnia medication containing two different barbiturates. Kanable,...

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Dudes - The Original Motion Picture Soundtrack Album (1987, MCA) "Warsaw Tuinal" on Spinning the Chamber (1995, Last Resort Records) "Equalizer" on Slam...

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a rug on the floor and a couple of boxes for furniture and took a few Tuinals and a few Seconals and I scooped up this guitar Joey gave me, this Dumpster...

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Chelmsford Royal Commission

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under deep sleep therapy. The drugs used in deep sleep therapy include Tuinal, Neulactil, Sodium Amyta, Placidyl, and Serenace. All of these substances...

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