Zonisamide, sold under the brand name Zonegran among others, is a medication used to treat the symptoms of epilepsy and Parkinson's disease.[5][6] Chemically it is a sulfonamide. It serves as an anticonvulsant used primarily as an adjunctive therapy in adults with Parkinson's disease, partial-onset seizures; infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic and generalized tonic clonic seizure.[7] Despite this it is also sometimes used as a monotherapy for partial-onset seizures.[6][8]
In 2020, it was the 276th most commonly prescribed medication in the United States, with more than 1million prescriptions.[9][10]
^"Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017". Therapeutic Goods Administration (TGA). 21 June 2022. Retrieved 30 March 2024.
^"Zonegran- zonisamide capsule". DailyMed. 20 August 2021. Archived from the original on 27 January 2021. Retrieved 19 July 2022.
^"Zonisade- zonisamide suspension". DailyMed. 15 July 2022. Retrieved 21 January 2023.
^ abcdeCite error: The named reference TGA was invoked but never defined (see the help page).
^Grover ND, Limaye RP, Gokhale DV, Patil TR (November–December 2013). "Zonisamide: a review of the clinical and experimental evidence for its use in Parkinson's disease". Indian Journal of Pharmacology. 45 (6): 547–55. doi:10.4103/0253-7613.121266. PMC 3847242. PMID 24347760.
^ abBrayfield A, ed. (8 March 2016). "Zonisamide: Martindale: The Complete Drug Reference". MedicinesComplete. London, UK: Pharmaceutical Press. Archived from the original on 27 August 2021. Retrieved 19 August 2017.
^Souney P, Mutnick A, Shargel L (2007). Comprehensive Pharmacy Review (6th ed.). Williams & Wilkins. p. 988. ISBN 9780781765619. OCLC 869677890.
^Cite error: The named reference AMH was invoked but never defined (see the help page).
^"The Top 300 of 2020". ClinCalc. Retrieved 7 October 2022.
^"Zonisamide - Drug Usage Statistics". ClinCalc. Retrieved 7 October 2022.
Zonisamide, sold under the brand name Zonegran among others, is a medication used to treat the symptoms of epilepsy and Parkinson's disease. Chemically...
gabapentin, levetiracetam, lacosamide, pregabalin, valproic acid and zonisamide are examples of non-enzyme-inducing ASMs. The following hormonal contraceptives...
oximes are key intermediates in the synthesis of the anti-convulsant drug zonisamide. Tisocromide is an example of a sultone. Mesylate (methanesulfonate),...
anxiety Zoloft (sertraline) – an antidepressant of the SSRI class Zonegran (zonisamide) – an anticonvulsant used to treat other seizures Zulresso (brexanolone)...
the diet is combined with the vagus nerve stimulator or with the drug zonisamide, and that the diet may be less successful in children receiving phenobarbital...
be strong enough to cause metabolic acidosis of clinical importance. Zonisamide is another sulfur containing antiseizure drug that weakly inhibits carbonic...
risperidone, paliperidone, ocaperidone, and iloperidone) and the anticonvulsant zonisamide. Its aromaticity makes it relatively stable; however, it is only weakly...
in larger doses for recreation, the antiepileptic drugs phenytoin and zonisamide, and the anticonvulsant drug lamotrigine, as well as the hypnotic drug...
yohimbine – used to reverse effects of xylazine, also called an "antidote" to xylazine zonisamide – anti-convulsant used for seizures Animal Drugs @ FDA...
Global Information
