Chemical structure of tropane which forms the core of tropane alkaloidsChemical structure and phylogeny of tropane alkaloids. Displayed are 3 chemical compounds that occur as natural products in 5 plant species
Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure.[1] Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloids such as cocaine and scopolamine are notorious for their psychoactive effects, related usage and cultural associations.[2][3][4][5][6][7] Particular tropane alkaloids such as these have pharmacological properties and can act as anticholinergics or stimulants.
^O’Hagan, David (2000). "Pyrrole, pyrrolidine, pyridine, piperidine and tropane alkaloids (1998 to 1999)". Natural Product Reports. 17 (5): 435–446. doi:10.1039/a707613d. PMID 11072891.
^Hesse M (2002). Alkaloids: Nature's Curse or Blessing?. Weinheim: Wiley-VCH. p. 304. ISBN 978-3-906390-24-6.
^Ryzik M (10 June 2007). "Cocaine: Hidden in Plain Sight". The New York Times. Archived from the original on 11 August 2017. Retrieved 18 May 2017.
^"The Buyers – A Social History of America's Most Popular Drugs". FRONTLINE. PBS. Archived from the original on 14 May 2017. Retrieved 18 May 2017.
^Anderson L. "Devil's Breath: Urban Legend or the World's Most Scary Drug?". Drugs.com. Retrieved 9 July 2019.
^Fatur, Karsten (June 2020). ""Hexing Herbs" in Ethnobotanical Perspective: A Historical Review of the Uses of Anticholinergic Solanaceae Plants in Europe". Economic Botany. 74 (2): 140–158. doi:10.1007/s12231-020-09498-w. ISSN 0013-0001. S2CID 220844064.
^Rätsch, Christian, The Encyclopedia of Psychoactive Plants: Ethnopharmacology and Its Applications pub. Park Street Press 2005
Tropanealkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane...
(anticholinergic syndrome) with a potentially fatal outcome. It contains tropanealkaloids which are responsible for the psychoactive effects, and may be severely...
Tropane is a nitrogenous bicyclic organic compound. It is mainly known for the other alkaloids derived from it, which include atropine and cocaine, among...
foliage and berries are extremely toxic when ingested, containing tropanealkaloids. These toxins include atropine, scopolamine, and hyoscyamine, which...
French: cocaïne, from Spanish: coca, ultimately from Quechua: kúka) is a tropanealkaloid that acts as a central nervous system (CNS) stimulant. As an extract...
diverse range of alkaloids. To humans, these alkaloids can be desirable, toxic, or both. The tropanes are the most well-known of the alkaloids found in the...
prohibited. Solanaceous tribes with a similar chemistry (i.e. a similar tropanealkaloid content), include the Hyoscyameae, containing such well-known toxic...
prominent tropanealkaloid found in coca leaves. It is metabolite of cocaine, and may be used as a precursor for it. It also occurs as minor alkaloid in roots...
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds...
hyoscine, or Devil's Breath, is a natural or synthetically produced tropanealkaloid and anticholinergic drug that is used as a medication to treat motion...
Atropine is a tropanealkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types...
species are among the most toxic of ornamental plants, containing tropanealkaloids of the type also responsible for the toxicity and deliriant effects...
form of the tropanealkaloids scopolamine, atropine, and hyoscyamine. Other, lesser known plant sources of scopolamine and related tropanes include Scopolia...
Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropanealkaloid and plant toxin. It is a secondary metabolite found in certain plants...
Ecgonine (tropane derivative) is a tropanealkaloid found naturally in coca leaves. It has a close structural relation to cocaine: it is both a metabolite...
of hairiness. Because mandrakes contain deliriant hallucinogenic tropanealkaloids and the shape of their roots often resembles human figures, they have...
africana: Up to 10% Iboga alkaloids Pilosella officinarum[citation needed] Erythroxylum pungens: DMT Acacia acuminata, Up to 1.5% alkaloids, mainly consisting...
hydrolysis of atropine or other solanaceous alkaloids. Pseudotropine Atropine Tropinone Tropanealkaloid "8-Methyl-8-azabicyclo[3.2.1]octan-3-ol". https://www...
1016/0031-9422(88)87026-2. Humphrey AJ, O'Hagan D (October 2001). "Tropanealkaloid biosynthesis. A century old problem unresolved". Nat Prod Rep. 18 (5):...
neurologic effects of the alkaloid protopine are qualitatively comparable to those of the well-known delirient tropanealkaloid atropine. The 45-year-old...
analyses having revealed the presence of the tropanealkaloid tropinone and the pyrrolidine alkaloid hygrine (0.1%, in the root). Withanolides are found...
witches. The specific nightshades used in such concoctions were usually tropanealkaloid-containing species belonging to the Old World tribes Hyoscyameae and...
Datumetine is a tropanealkaloid found in leaves of Datura metel. It is said to modulate NMDA receptor and thus causes memory loss. It also causes epileptic...
ornamental and for its medicinal properties, the latter being due to its tropanealkaloid content. Like its hardier and smaller-flowered relative Datura stramonium...
aphrodisiac in Brazilian herbal medicine. It contains a class of tropanealkaloids called catuabines. Wikimedia Commons has media related to Erythroxylum...
myopia is also available in China. Anisodamine is a naturally occurring tropanealkaloid found in some plants of the family Solanaceae including Datura. Its...
Catuabines are a group of tropanealkaloids, isolated from Erythroxylum vaccinifolium, which are used in the preparation of the drug Catuaba (which in...
Coca alkaloids are the alkaloids found in the coca plant, Erythroxylum coca. They are predominantly of either the pyrrolidine or the tropane types. Benzoylecgonine...
Scopine is a tropanealkaloid found in a variety of plants including Mandragora root, Senecio mikanioides (Delairea odorata), Scopolia carniolica, and...
Hydroxytropacocaine Benzoylecgonine p-Fluorotropacocaine Indatraline Tropanealkaloid Jowett, H. A. D.; Pyman, F. L. (1909). "CXVI.?Relation between chemical...
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