Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics such as LSD and dissociatives such as ketamine, due to their primary effect of causing delirium, as opposed to the more lucid (i.e. rational thought is preserved better, including the skepticism about the hallucinations) and less disturbed states produced by other types of hallucinogens.[1] The term generally refers to anticholinergic drugs, which are substances that inhibit the function of the neurotransmitter acetylcholine. Common examples of deliriants include plants of the genera Datura and Brugmansia (both containing scopolamine) as well as higher than recommended dosages of diphenhydramine (Benadryl).[2][3] A number of plant deliriants such as that of the Solanaceae family, particularly in the Americas have been used by some indigenous cultures to reach delirious and altered states for traditions or rituals, such as rites of passage, divination or communicating with the ancestors.[4] Despite their long history of use, deliriants are the least-studied class of hallucinogens in terms of their behavioral and neurological effects.[5]
^Duncan, D. F., and Gold, R. S. (1982). Drugs and the Whole Person. New York: John Wiley & Sons
^"Datura reports on Erowid". Retrieved 2013-05-07.
^Forest E (27 July 2008). "Atypical Drugs of Abuse". Articles & Interviews. Student Doctor Network. Archived from the original on 27 May 2013.
^Kennedy, David O. (2014). "The Deliriants - The Nightshade (Solanaceae) Family". Plants and the Human Brain. New York: Oxford University Press. pp. 131–137. ISBN 978-0-19-991401-2. LCCN 2013031617. Archived from the original on 2021-09-17. Retrieved 2021-09-17.
^Volgin, A. D.; Yakovlev, O. A.; Demin, K. A.; Alekseeva, P. A.; Kyzar, E. J.; Collins, C.; Nichols, D. E.; Kalueff, A. V. (16 October 2018). "Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models". ACS Chemical Neuroscience. 10 (1): 143–154. doi:10.1021/acschemneuro.8b00433. PMID 30252437. S2CID 52824516.
Deliriants are a subclass of hallucinogen. The term was coined in the early 1980s to distinguish these drugs from psychedelics such as LSD and dissociatives...
hallucinogens can be categorized as either being psychedelics, dissociatives, or deliriants. The word hallucinogen is derived from the word hallucination. The term...
which means it also works as a deliriant at much higher than recommended doses as a result. Its sedative and deliriant effects have led to some cases...
which means it also works as a deliriant at much higher than recommended doses as a result. Its sedative and deliriant effects have led to some cases...
psychoactive alkaloids. D. wrightii is classified as an anticholinergic deliriant. German botanist Eduard August von Regel described the species in 1859...
further treatment for intoxication. Though sometimes referred to as a deliriant and while muscarine was first isolated from A. muscaria and as such is...
substances (often the paralyzing pufferfish venom tetrodotoxin and the strong deliriant Datura), which rendered him helpless and seemingly dead. The greatest...
its sedative effects. This also means high or toxic doses can act as a deliriant. Promethazine was made in the 1940s by a team of scientists from Rhône-Poulenc...
may lead to loss of consciousness.[citation needed] Pheniramine is a deliriant (hallucinogen) in toxic doses. Recreational use of Coricidin for the dissociative...
can act as anticholinergics or stimulants. Anticholinergic drugs and deliriants: Atropine, racemic hyoscyamine, from the deadly nightshade (Atropa belladonna)...
(family Solanaceae), a poisonous plant sacred to Shiva with powerful deliriant properties, were sometimes used by thugs to induce drowsiness or stupefaction...
psychotic behavior in its users which may result in medical intervention. Deliriant drugs (muscarinic acetylcholine receptor antagonists) such as BZ (QNB)...
them to do his bidding, such as manual labor. The victim is often given deliriant drugs, mainly Datura stramonium, where they enter a detached, somewhat...
and a remedy for infertility. Larger doses act as an entheogen of the deliriant class, having the potential to cause profound confusion and dysphoria...
family, which historically have been used as psychoactive drugs (known as deliriants) due to their antimuscarinic-induced hallucinogenic effects in higher...
folklore. Shadow people are commonly reported by people under the effects of deliriant substances such as datura, diphenhydramine, and benzydamine. Finally,...
(8-chlorotheophylline/diphenhydramine) is occasionally used in higher doses as a deliriant. The prescription medicine Adderall (dextroamphetamine sulfate/amphetamine...
medicine for its richness in tropane alkaloids with anticholinergic, deliriant, antispasmodic and mydriatic properties. The specific name acuminata signifies...
in the United States under the brand name Benadryl), which acts as a deliriant in high doses. The challenge, which reportedly spread via the social media...
containing tropane alkaloids of the type also responsible for the toxicity and deliriant effects of both jimsonweed and the infamous deadly nightshade. All seven...
considered traditional witches' herbs and poisons. Datura is considered a deliriant. Due to the potent combination of anticholinergic substances it contains...