The glutamate receptor, metabotropic 1, also known as GRM1, is a human gene which encodes the metabotropic glutamate receptor 1 (mGluR1) protein.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000152822 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000019828 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Stephan D, Bon C, Holzwarth JA, Galvan M, Pruss RM (1996). "Human metabotropic glutamate receptor 1: mRNA distribution, chromosome localization and functional expression of two splice variants". Neuropharmacology. 35 (12): 1649–1660. doi:10.1016/S0028-3908(96)00108-6. PMID 9076744. S2CID 37222391.
^Makoff AJ, Phillips T, Pilling C, Emson P (September 1997). "Expression of a novel splice variant of human mGluR1 in the cerebellum". NeuroReport. 8 (13): 2943–2947. doi:10.1097/00001756-199709080-00027. PMID 9376535. S2CID 28116484.
and 25 Related for: Metabotropic glutamate receptor 1 information
The glutamatereceptor, metabotropic1, also known as GRM1, is a human gene which encodes the metabotropicglutamatereceptor1 (mGluR1) protein. L-glutamate...
The metabotropicglutamatereceptors, or mGluRs, are a type of glutamatereceptor that are active through an indirect metabotropic process. They are members...
Metabotropicglutamatereceptor 2 (mGluR2) is a protein that, in humans, is encoded by the GRM2 gene. mGluR2 is a G protein-coupled receptor (GPCR) that...
Metabotropicglutamatereceptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of...
Metabotropicglutamatereceptor 5 is an excitatory Gq-coupled G protein-coupled receptor predominantly expressed on the postsynaptic sites of neurons....
Metabotropicglutamatereceptor 7 is a protein that in humans is encoded by the GRM7 gene. L-glutamate is the major excitatory neurotransmitter in the...
Glutamatereceptor, metabotropic 6, also known as GRM6 or mGluR6, is a protein which in humans is encoded by the GRM6 gene. L-glutamate is the major excitatory...
Metabotropicglutamatereceptor 8 is a protein that in humans is encoded by the GRM8 gene. L-glutamate is the major excitatory neurotransmitter in the...
Metabotropicglutamatereceptor 3 (mGluR3) is an inhibitory Gi/G0-coupled G-protein coupled receptor (GPCR) generally localized to presynaptic sites of...
Glutamatereceptors are synaptic and non synaptic receptors located primarily on the membranes of neuronal and glial cells. Glutamate (the conjugate base...
A metabotropicreceptor, also referred to by the broader term G-protein-coupled receptor, is a type of membrane receptor that initiates a number of metabolic...
The metabotropicglutamatereceptors such as mGluR4 and mGluR1 can be easily activated at glutamate concentration levels found in food. Glutamate is ubiquitous...
and metabotropic (G-protein coupled) receptors. In the opposing postsynaptic cell, glutamatereceptors, such as the NMDA receptor or the AMPA receptor, bind...
message (i.e. metabotropicreceptors do not have channels). There are several kinds of metabotropicreceptors, including G protein-coupled receptors. Ionotropic...
receptor (also known as the NMDA receptor or NMDAR), is a glutamatereceptor and predominantly Ca2+ ion channel found in neurons. The NMDA receptor is...
Ionotropic glutamatereceptors (iGluRs) are ligand-gated ion channels that are activated by the neurotransmitter glutamate. They mediate the majority...
agonist of the AMPA, kainate, and group I metabotropicglutamatereceptors. It is one of the most potent AMPA receptor agonists known. It causes excitotoxicity...
Kainate receptors, or kainic acid receptors (KARs), are ionotropic receptors that respond to the neurotransmitter glutamate. They were first identified...
mGluR3) metabotropicglutamatereceptors. It is inactive at group III mGluRs. Ibotenic acid also acts as a weak agonist of the AMPA and kainate receptors. In...
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropicreceptors, that are linked...
(2021-01-11). "Mutations in MetabotropicGlutamateReceptor1 Contribute to Natural Short Sleep Trait". Current Biology. 31 (1): 13–24.e4. doi:10.1016/j...
acid receptor (also known as AMPA receptor, AMPAR, or quisqualate receptor) is an ionotropic transmembrane receptor for glutamate (iGluR) and predominantly...
Group II metabotropicglutamatereceptors in humans. It is also known to be a potent VGLUT inhibitor, thereby preventing the movement of glutamate from the...
acts as a positive allosteric modulator selective for the metabotropicglutamatereceptor subtype mGluR5. It has antipsychotic effects in animal models...
Global Information
