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Sulfonylurea information


General structural formula of a sulfonylurea. The functional group consists of a sulfonyl group and a N-substituted ureylene group

Sulfonylureas or sulphonylureas are a class of organic compounds used in medicine and agriculture. The functional group consists of a sulfonyl group (-S(=O)2) with its sulphur atom bonded to a nitrogen atom of a ureylene group (N,N-dehydrourea, a dehydrogenated derivative of urea). The side chains R1 and R2 distinguish various sulfonylureas. Sulfonylureas are the most widely used herbicide.

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Sulfonylurea

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Sulfonylureas or sulphonylureas are a class of organic compounds used in medicine and agriculture. The functional group consists of a sulfonyl group (-S(=O)2)...

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Gliclazide

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Gliclazide, sold under the brand name Diamicron among others, is a sulfonylurea type of anti-diabetic medication, used to treat type 2 diabetes. It is...

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Sulfonylurea receptor

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molecular biology, the sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of antidiabetic drugs...

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Glimepiride

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Glimepiride is an antidiabetic medication within the sulfonylurea class, primarily prescribed for the management of type 2 diabetes. It is regarded as...

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Hypoglycemia

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hypoglycemia is medications used to treat diabetes such as insulin, sulfonylureas, and biguanides. Risk is greater in diabetics who have eaten less than...

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Glibenclamide

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during pregnancy but can be used during breastfeeding. It is in the sulfonylureas class of medications and works by increasing the release of insulin...

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Diazoxide

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and leucine sensitivity. It can also be used in refractory cases of sulfonylurea toxicity. It is generally taken by mouth. Common side effects include...

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Glipizide

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brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. It is used together with a diabetic...

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Exenatide

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antidiabetic medication. It is a treatment option after metformin and sulfonylureas. It is given by injection under the skin. Common side effects include...

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Metformin

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metformin reduces body weight in people with type 2 diabetes in contrast to sulfonylureas, which are associated with weight gain. Some evidence shows that metformin...

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Chlorpropamide

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to the sulfonylurea class of organic compounds. It is used to treat diabetes mellitus type 2. It is a long-acting first-generation sulfonylurea. Like other...

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Diabetes medication

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metformin, are currently available as generics. Sulfonylureas bind strongly to plasma proteins. Sulfonylureas are useful only in type 2 diabetes, as they...

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Loxoprofen

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may also increase the plasma concentration of warfarin, methotrexate, sulfonylurea derivatives and lithium salts, so care should be taken when loxoprofen...

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Sitagliptin

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the United Kingdom it is listed as less preferred than metformin or a sulfonylurea. It is taken by mouth. It is also available in the fixed-dose combination...

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Dulaglutide

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with other medicines for type 2 diabetes, in particular metformin, sulfonylureas, thiazolidinediones, and insulin taken concomitantly with meals. The...

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Canagliflozin

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Per the British National Formulary it is also less preferred than a sulfonylurea as of 2019, while the American Diabetes Association and European Association...

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Pioglitazone

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medication used to treat type 2 diabetes. It may be used with metformin, a sulfonylurea, or insulin. Use is recommended together with exercise and diet. It is...

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Empagliflozin

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increase the risk of low blood sugar when it is used together with a sulfonylurea or insulin. When used by itself or in addition to metformin it does not...

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List of sulfonamides

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This is a list of sulfonamides used in medicine. Short-acting Sulfacetamide Sulfadiazine Sulfadimidine Sulfafurazole (sulfisoxazole) Sulfisomidine (sulfaisodimidine)...

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Minoxidil

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and potentiates HGF and IGF-1 actions by the activation of uncoupled sulfonylurea receptor on the plasma membrane of dermal papilla cells. A number of...

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Semaglutide

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Metformin/gemigliptin Metformin/repaglinide Metformin/sulfonylureas Metformin/teneligliptin Phenformin/sulfonylureas Pioglitazone/alogliptin Pioglitazone/glimepiride...

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Tirzepatide

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Metformin/gemigliptin Metformin/repaglinide Metformin/sulfonylureas Metformin/teneligliptin Phenformin/sulfonylureas Pioglitazone/alogliptin Pioglitazone/glimepiride...

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ABCC8

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variants have not been fully described. ATP-binding cassette transporter Sulfonylurea receptor GRCh38: Ensembl release 89: ENSG00000006071 – Ensembl, May 2017...

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Glossary of diabetes

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may take these pills. See also: Oral hypoglycemic agents. One of the sulfonylurea drugs. (Dymelor Dimelor) Acetone A byproduct of fat metabolism. One of...

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Diabetes

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type 2 diabetes. These include agents that increase insulin release (sulfonylureas), agents that decrease absorption of sugar from the intestines (acarbose)...

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Tolazamide

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lowering drug used for people with Type 2 diabetes. It is part of the sulfonylurea family (ATC A10BB). para-Toluenesulfonamide is converted to its carbamate...

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