Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Solasonine is a glycoalkaloid that is found in Solanum plants of the family Solanaceae.[1] Solasonine is a poisonous chemical compound when used at high levels. It is a glycoside of solasodine. Glycoalkaloids such as Solasonine have various applications including pharmacology, cancer treatments and even a role as a pesticide.
High levels of glycoalkaloids are toxic to humans due to their ability to disrupt cell-membrane function.[2] There is a loss of membrane integrity which puts the cell at risk for apoptosis (cell death) due to the ability of any chemical coming into contact with the cell.
Solasonine was one component of the unsuccessful experimental cancer drug candidate Coramsine.
^Everist, S.L. (1981). Poisonous Plants of Australia. Angus & Robertson. ISBN 0-207-14228-9.
^Al Sinani, S.S.S.; Eltayeb, E.A. (September 2017). "The steroidal glycoalkaloids solamargine and solasonine in Solanum plants". South African Journal of Botany. 112: 253–269. doi:10.1016/j.sajb.2017.06.002. ISSN 0254-6299.
Solasonine is a glycoalkaloid that is found in Solanum plants of the family Solanaceae. Solasonine is a poisonous chemical compound when used at high levels...
and solamargine. Other toxins present in the plant include chaconine, solasonine, solanigrine, gitogenin and traces of saponins, as well as the tropane...
occurs in plants of the family Solanaceae such as potatoes and tomatoes. Solasonine and solamargine are glycoalkaloid derivatives of solasodine. Solasodine...
to develop Coramsine, a 1:1 mixture of the alkaloids solamargine and solasonine extracted from Solanum linnaeanum, as a cancer drug. Preliminary clinical...
about 1.5% of glycoalkaloids in its dried fruits, chiefly solamargine and solasonine, mostly in the peel and seeds. Extracts have been shown to kill in vitro...
María-Cortes; Yokoyama, Wallace E.; Hong, Yun-Jeong; Prohens, Jaime (2010). "Α-Solasonine and α-Solamargine Contents of Gboma (Solanum macrocarpon L.) and Scarlet...
Rayburn, J. R.; et al. (1998). "Developmental toxicology of solamargine and solasonine glycoalkaloids in frog embryos". Food and Chemical Toxicology. 36 (5):...
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