Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Pyruvic acid (IUPAC name: 2-oxopropanoic acid, also called acetoic acid) (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, CH3COCOO−, is an intermediate in several metabolic pathways throughout the cell.
Pyruvic acid can be made from glucose through glycolysis, converted back to carbohydrates (such as glucose) via gluconeogenesis, or converted to fatty acids through a reaction with acetyl-CoA.[3] It can also be used to construct the amino acid alanine and can be converted into ethanol or lactic acid via fermentation.
Pyruvic acid supplies energy to cells through the citric acid cycle (also known as the Krebs cycle) when oxygen is present (aerobic respiration), and alternatively ferments to produce lactate when oxygen is lacking.[4]
^ abNomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 748. doi:10.1039/9781849733069-FP001 (inactive 2024-04-10). ISBN 978-0-85404-182-4.{{cite book}}: CS1 maint: DOI inactive as of April 2024 (link)
^Dawson, R. M. C.; et al. (1959). Data for Biochemical Research. Oxford: Clarendon Press.
^Fox, Stuart Ira (2011). Human Physiology (12th ed.). McGraw=Hill. p. 146.[ISBN missing]
^Ophardt, Charles E. "Pyruvic Acid - Cross Roads Compound". Virtual Chembook. Elmhurst College. Archived from the original on July 31, 2018. Retrieved April 7, 2017.
Pyruvicacid (IUPAC name: 2-oxopropanoic acid, also called acetoic acid) (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and...
prodrug scaffold. Important representatives: pyruvicacid, pervasive intermediate in metabolism. oxaloacetic acid, a component of the Krebs cycle. alpha-ketoglutarate...
Sodium pyruvate is a salt of the conjugate anion form of pyruvicacid, known as pyruvate. It is commonly added to cell culture media as an additional source...
compound with the formula CH3C(O)CHO. It is a reduced derivative of pyruvicacid. It is a reactive compound that is implicated in the biology of diabetes...
fatty acids exuded by mammalian skin, together with lactic acid and pyruvicacid, is distinctive and enables animals with a keen sense of smell to differentiate...
produce pyruvicacid from glucose metabolism. Some enterics subsequently use the mixed acid pathway to metabolize pyruvicacid to other acids, such as...
synthesis by reacting phenylhydrazine with pyruvicacid followed by decarboxylation of the formed indole-2-carboxylic acid. This has also been accomplished in...
from pyruvicacid and alpha-ketoglutarate. Enzymes involved in this biosynthesis include acetolactate synthase (also known as acetohydroxy acid synthase)...
diesters with diamines gives cyclic diamides. α-Keto-acids and -esters are well known. Pyruvicacid (CH3C(O)CO2H) is the parent α-ketoacid. Its conjugate...
in the liver where it is converted into lactic acid, which can, in turn, be oxidized into pyruvicacid, and only then into acetyl-CoA. Ketone bodies have...
Neuraminic acid may also be visualized as the product of an aldol-condensation of pyruvicacid and D-mannosamine (2-amino-2-deoxy-mannose). Neuraminic acid does...
glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. Lactic acid and pyruvicacid are later derived from these molecules. "Trioses - Three Carbon...
Bromopyruvic acid is the organic compound with the formula BrCH2COCO2H. This colorless solid is the brominated derivative of pyruvicacid. It bears structural...
decarboxylation of pyruvicacid to acetaldehyde. It is also called 2-oxo-acid carboxylase, alpha-ketoacid carboxylase, and pyruvic decarboxylase. In anaerobic...
the action of the enzyme enolase on 2-phosphoglyceric acid. Metabolism of PEP to pyruvicacid by pyruvate kinase (PK) generates adenosine triphosphate...
Carboxylic acids are organic acids characterized by a carboxyl (-COOH) functional group. The naming of these compounds is governed by IUPAC nomenclature...
process converts one molecule of glucose into two molecules of pyruvate (pyruvicacid), generating energy in the form of two net molecules of ATP. Four molecules...
Glyoxylic acid or oxoacetic acid is an organic compound. Together with acetic acid, glycolic acid, and oxalic acid, glyoxylic acid is one of the C2 carboxylic...
have a sweeter flavor than white or yellow onions due to low levels of pyruvicacid and sulfur compounds. They are often consumed raw (and can be added to...
μmol/gfw (micromoles per gram fresh weight). It is named after pyruvicacid, the alpha-keto acid co-product created in the biochemical pathway that forms...
α-Acetolactic acid is produced from two molecules of pyruvicacid by acetolactate synthase. α-Acetolactic acid can also be decarboxylated by alpha-acetolactate...
(NAD+). During the reaction, E1 participates in the decarboxylation of pyruvicacid, and then TPP connects the acetyl group after the reaction. The carbonyl...
carboxylic acid is an organic acid that contains a carboxyl group (−C(=O)−OH) attached to an R-group. The general formula of a carboxylic acid is often...
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